1.
Klin Med (Mosk)
; 65(9): 76-8, 1987 Sep.
Article
in Russian
| MEDLINE
| ID: mdl-3695317
2.
Gematol Transfuziol
; 31(8): 16-8, 1986 Aug.
Article
in Russian
| MEDLINE
| ID: mdl-3463519
3.
Vopr Kurortol Fizioter Lech Fiz Kult
; (6): 38-40, 1984.
Article
in Russian
| MEDLINE
| ID: mdl-6523789
4.
Urol Nefrol (Mosk)
; (4): 47-9, 1983.
Article
in Russian
| MEDLINE
| ID: mdl-6623751
5.
Probl Endokrinol (Mosk)
; 29(1): 11-5, 1983.
Article
in Russian
| MEDLINE
| ID: mdl-6835951
ABSTRACT
The blood and urine porphyrin content and porphyrin biosynthesis in the red blood cells after delta-amino levulinic acid (ALA) incubation, porphobilinogen and non-consumed ALA levels, porphobilinogen-synthetase activity were studied in 86 patients divided into 3 groups depending on diabetes severity. Porphyrin separation was investigated by means of thin-layer chromatography. It was found that porphyrin biosynthesis decreases in all diabetics at the early periods of the disease, not depending on its severity. Porphyrin biosynthesis is lowered during a phase of chronic renal insufficiency in patients with diabetic nephropathy. Porphyrin metabolic disorder is caused by hepatic dysfunction and diabetic nephropathy development.
Subject(s)
Diabetes Mellitus/metabolism , Porphyrins/biosynthesis , Adult , Aged , Diabetes Mellitus/pathology , Diabetic Nephropathies/metabolism , Diabetic Nephropathies/pathology , Female , Humans , Male , Middle Aged , Mitochondria, Liver/metabolism , Porphobilinogen Synthase/metabolism , Pyelonephritis/metabolism , Pyelonephritis/pathology
6.
Probl Gematol Pereliv Krovi
; 27(2): 14-6, 1982 Feb.
Article
in Russian
| MEDLINE
| ID: mdl-7063465
7.
Urol Nefrol (Mosk)
; (6): 36-40, 1981.
Article
in Russian
| MEDLINE
| ID: mdl-7314313
Subject(s)
Kidney Diseases/blood , Metabolic Diseases/blood , Porphyrins/biosynthesis , Adolescent , Adult , Erythrocytes/metabolism , Female , Humans , Kidney Failure, Chronic/blood , Male , Middle Aged
8.
Probl Gematol Pereliv Krovi
; 26(9): 21-3, 1981 Sep.
Article
in Russian
| MEDLINE
| ID: mdl-7198228
Subject(s)
Infant, Newborn , Porphyrins/biosynthesis , Postpartum Period , Adolescent , Adult , Erythrocytes/metabolism , Female , Humans , Porphyrins/blood , Pregnancy
9.
Probl Gematol Pereliv Krovi
; 25(6): 44-6, 1980 Jun.
Article
in Russian
| MEDLINE
| ID: mdl-7393879