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Vopr Virusol ; 64(6): 262-267, 2019.
Article in Russian | MEDLINE | ID: mdl-32168439

ABSTRACT

Provision of infection security in transplantology and transfusiology is a challenging and significant problem that depends on the quality of medical donor selection and laboratory diagnosis of the blood collected. At present, a large number of blood-borne viruses are known; nevertheless, in Russia, the list of viral agents to be tested during the examination by the blood service boils down to three ones: HIV, hepatitis C and hepatitis B viruses. The review article demonstrates the need for implementation of additional laboratory tests for the agents of the priority healthcare-associated blood-borne infections (HAI) using a risk-based approach, i.e., on specified sites and in high risk groups. It presents a methodology for determination of a quantitative blood-induced infection residual risk (BIRR) index to be used while evaluating the efficiency of viral security provision in the blood service.


Subject(s)
Deltaretrovirus Infections/prevention & control , Disease Transmission, Infectious/prevention & control , HIV Infections/prevention & control , Hepatitis, Viral, Human/prevention & control , Herpes Simplex/prevention & control , Blood Transfusion , Deltaretrovirus Infections/diagnosis , Deltaretrovirus Infections/epidemiology , Deltaretrovirus Infections/virology , Disease Transmission, Infectious/statistics & numerical data , HIV Infections/diagnosis , HIV Infections/epidemiology , HIV Infections/virology , HIV-1/pathogenicity , HIV-1/physiology , HIV-2/pathogenicity , HIV-2/physiology , Hepacivirus/pathogenicity , Hepacivirus/physiology , Hepatitis B virus/pathogenicity , Hepatitis B virus/physiology , Hepatitis, Viral, Human/diagnosis , Hepatitis, Viral, Human/epidemiology , Hepatitis, Viral, Human/virology , Herpes Simplex/diagnosis , Herpes Simplex/epidemiology , Herpes Simplex/virology , Human T-lymphotropic virus 1/pathogenicity , Human T-lymphotropic virus 1/physiology , Human T-lymphotropic virus 2/pathogenicity , Human T-lymphotropic virus 2/physiology , Humans , Russia/epidemiology , Simplexvirus/pathogenicity , Simplexvirus/physiology , Tissue Transplantation
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