ABSTRACT
Chronic anticoagulant treatment is administered mostly for cardiological reasons. Cumarin derivatires are used in the majority of cases (Warfarin, Pelentan). It is necessary to monitor this treatment regularly and to control the dose according to the INR value. Different complications can occur; the haemorrhage represents a serious one. The authors discuss several aspects of anticoagulant therapy and possible prevention of the complications. The importance of the problems is demonstrated on the authors' clinical experience--two cases of haemorrhage after Warfarin administration simulating an acute surgical event.
Subject(s)
Anticoagulants/adverse effects , Hemorrhage/chemically induced , Abdomen, Acute/diagnosis , Abdomen, Acute/etiology , Abdominal Muscles , Aged , Aged, 80 and over , Ethyl Biscoumacetate/adverse effects , Female , Hematoma/chemically induced , Hemorrhage/diagnosis , Hemorrhage/prevention & control , Humans , Male , Retroperitoneal Space , Warfarin/adverse effectsABSTRACT
The author presents results of treatment of 262 patients with diabetic gangrene, necrosis and phlegmons; he mentions the complex of therapeutic measures incl. acral and high amputations, analyzes the causes of difficulties associated with therapy of ischaemic and infectious affections of the diabetic foot and possibilities how to improve the present unsatisfactory state of the problem.
