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Steroids ; 71(2): 116-9, 2006 Feb.
Article in English | MEDLINE | ID: mdl-16226287

ABSTRACT

Treatment of Delta 4-3-ketosteroids with m-chloroperbenzoic acid at 0 degrees C produced the corresponding steroidal seven-membered A-ring epoxy lactones. The adopted procedure allowed for efficient recovery and separation of the products with definite stereochemistry.


Subject(s)
Epoxy Compounds/chemical synthesis , Ketosteroids/chemistry , Lactones/chemical synthesis , Steroids/chemistry , Chlorobenzoates/chemistry , Epoxy Compounds/chemistry , Lactones/chemistry , Molecular Conformation , Oxidation-Reduction , Stereoisomerism
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