ABSTRACT
The platelet-rich plasma (PRP) has proved promising regarding its applicability in dermatology, especially in the healing of chronic ulcers. The autologous platelet-rich plasma is obtained by centrifuging the blood, so that the components are separated by density gradient. The final product is a gel rich in growth factors that act in tissue repair by activating fibroblasts and inducing extracellular matrix remodeling.
Subject(s)
Platelet-Rich Plasma , Skin Ulcer/therapy , Wound Healing , Aged , Blood Transfusion, Autologous/methods , Chronic Disease , Female , Gels/therapeutic use , Humans , Platelet Transfusion/methods , Skin Ulcer/pathology , Treatment OutcomeABSTRACT
The platelet-rich plasma (PRP) has proved promising regarding its applicability in dermatology, especially in the healing of chronic ulcers. The autologous platelet-rich plasma is obtained by centrifuging the blood, so that the components are separated by density gradient. The final product is a gel rich in growth factors that act in tissue repair by activating fibroblasts and inducing extracellular matrix remodeling.
