ABSTRACT
Injury to the heart in blunt chest trauma is dependent on a number of factors. Symptoms are often non-specific, and there is no gold standard test for diagnosis. Injuries to small areas of the myocardium may only be identified at autopsy. We report a 38 year old man who sustained a number of injuries in a road traffic accident, and in whom the single clinical or ECG abnormality was a left bundle branch block (LBBB); he had a myocardial injury rated as grade II. The patient was treated for his injuries and later discharged. As this is a difficult diagnosis, algorithms of blunt chest trauma may save time and money by avoiding misleading diagnosis and unnecessary monitoring and admissions.
Subject(s)
Bundle-Branch Block/etiology , Contusions/complications , Heart Injuries/complications , Adult , Bundle-Branch Block/therapy , Contusions/therapy , Drainage/methods , Electrocardiography , Emergencies , Heart Injuries/therapy , Humans , Male , Treatment OutcomeABSTRACT
Controversial laboratory results and the now discredited "wire code paradox" suggest that epidemiologists might miss something if they measured only 60 Hz fields and summarize time series of exposure with only a time integral. This has led to the question of how else the exposure issue could be addressed. This paper proposes a potential answer to this question by borrowing concepts from pharmacology. The paper briefly explores how the limitations of current analysis can lead to poor public policy decisions. The paper then uses a pharmacological analogy to highlight such concepts as "mixture," "ingredient," "dose duration," "dosing schedule," and "windows of biological vulnerability" to guide an epidemiologist in choosing what to measure. The authors point out that any candidate "ingredient" or exposure metric must be associated with wire code or spot measurements if it is to explain previous epidemiological associations. This helps eliminate many "ingredients" and exposure metrics from consideration. The authors then describe how they applied these concepts in the design of a prospective study of miscarriage and EMF exposure.
Subject(s)
Electromagnetic Fields/adverse effects , Abortion, Spontaneous/epidemiology , Abortion, Spontaneous/etiology , California/epidemiology , Environmental Exposure , Epidemiologic Methods , Female , Humans , Pregnancy , Prospective Studies , Public Health , Public Policy , Time FactorsSubject(s)
Electromagnetic Fields/adverse effects , Leukemia, Radiation-Induced/epidemiology , Neoplasms, Radiation-Induced/epidemiology , Data Interpretation, Statistical , Humans , Leukemia, Radiation-Induced/etiology , Neoplasms, Radiation-Induced/etiology , Odds Ratio , Radiation Dosage , Sensitivity and SpecificityABSTRACT
A case of HELLP-syndrome is reported and attention called to the importance of early recognition of the syndrome whose clinical characteristics at times delay intervention that can be important for the wellbeing of mother and foetus.
Subject(s)
Hemolysis/physiology , Liver/enzymology , Pregnancy Complications, Hematologic/physiopathology , Thrombocytopenia/complications , Adult , Female , Humans , Platelet Count , Pregnancy , Pregnancy Complications, Hematologic/blood , Pregnancy Complications, Hematologic/enzymology , Syndrome , Thrombocytopenia/blood , Thrombocytopenia/enzymologyABSTRACT
A case of hematocolpos due to imperforate hymen in a 13-year-old girl has been studied by means of ultrasounds. The images speak clearly. The primary amenorrhoea combined with abdominal colics should always suggest to the surgeon and the specialist in paediatrics the possible existence of a genital malformation.
Subject(s)
Hematocolpos/etiology , Hymen , Ultrasonography , Adolescent , Female , HumansABSTRACT
On the basis of seven cases of suspected liver pathology, an albeit modest contribution has been made to the significance and diagnostic possibilities of ultrasonographic investigation of the upper abdomen. In four cases, ultrasound findings were confirmed by scintigraphy and in three cases by necropsy and histological reports.