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1.
Comput Biol Med ; 158: 106876, 2023 05.
Article in English | MEDLINE | ID: mdl-37030266

ABSTRACT

The paper proposes a methodology based on Natural Language Processing (NLP) and Sentiment Analysis (SA) to get insights into sentiments and opinions toward COVID-19 vaccination in Italy. The studied dataset consists of vaccine-related tweets published in Italy from January 2021 to February 2022. In the considered period, 353,217 tweets have been analyzed, obtained after filtering 1,602,940 tweets with the word "vaccin". A main novelty of the approach is the categorization of opinion holders in four classes, Common users, Media, Medicine, Politics, obtained by applying NLP tools, enhanced with large-scale domain-specific lexicons, on the short bios published by users themselves. Feature-based sentiment analysis is enriched with an Italian sentiment lexicon containing polarized words, expressing semantic orientation, and intensive words which give cues to identify the tone of voice of each user category. The results of the analysis highlighted an overall negative sentiment along all the considered periods, especially for the Common users, and a different attitude of opinion holders towards specific important events, such as deaths after vaccination, occurring in some days of the examined 14 months.


Subject(s)
Attitude , COVID-19 Vaccines , Sentiment Analysis , Social Media , Humans , COVID-19/epidemiology , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Italy/epidemiology , Social Media/statistics & numerical data
2.
Artif Intell Med ; 128: 102286, 2022 06.
Article in English | MEDLINE | ID: mdl-35534142

ABSTRACT

The outbreak of novel corona virus 2019 (COVID-19) has been treated as a public health crisis of global concern by the World Health Organization (WHO). COVID-19 pandemic hugely affected countries worldwide raising the need to exploit novel, alternative and emerging technologies to respond to the emergency created by the weak health-care systems. In this context, Artificial Intelligence (AI) techniques can give a valid support to public health authorities, complementing traditional approaches with advanced tools. This study provides a comprehensive review of methods, algorithms, applications, and emerging AI technologies that can be utilized for forecasting and diagnosing COVID-19. The main objectives of this review are summarized as follows. (i) Understanding the importance of AI approaches such as machine learning and deep learning for COVID-19 pandemic; (ii) discussing the efficiency and impact of these methods for COVID-19 forecasting and diagnosing; (iii) providing an extensive background description of AI techniques to help non-expert to better catch the underlying concepts; (iv) for each work surveyed, give a detailed analysis of the rationale behind the approach, highlighting the method used, the type and size of data analyzed, the validation method, the target application and the results achieved; (v) focusing on some future challenges in COVID-19 forecasting and diagnosing.


Subject(s)
COVID-19 , Pandemics , Artificial Intelligence , COVID-19/epidemiology , Humans , Machine Learning , SARS-CoV-2
3.
Entropy (Basel) ; 23(2)2021 Feb 05.
Article in English | MEDLINE | ID: mdl-33562478

ABSTRACT

The Special Issue on "Computation in Complex Networks" focused on gathering highly original papers in the field of current complex network research [...].

4.
Appl Netw Sci ; 5(1): 91, 2020.
Article in English | MEDLINE | ID: mdl-33225045

ABSTRACT

Initially emerged in the Chinese city Wuhan and subsequently spread almost worldwide causing a pandemic, the SARS-CoV-2 virus follows reasonably well the Susceptible-Infectious-Recovered (SIR) epidemic model on contact networks in the Chinese case. In this paper, we investigate the prediction accuracy of the SIR model on networks also for Italy. Specifically, the Italian regions are a metapopulation represented by network nodes and the network links are the interactions between those regions. Then, we modify the network-based SIR model in order to take into account the different lockdown measures adopted by the Italian Government in the various phases of the spreading of the COVID-19. Our results indicate that the network-based model better predicts the daily cumulative infected individuals when time-varying lockdown protocols are incorporated in the classical SIR model.

5.
IEEE Trans Cybern ; 50(12): 4997-5009, 2020 Dec.
Article in English | MEDLINE | ID: mdl-30668490

ABSTRACT

Methods for detecting the community structure in complex networks have mainly focused on network topology, neglecting the rich content information often associated with nodes. In the last few years, the compositional dimension contained in many real-world networks has been recognized fundamental to find network divisions which better reflect group organization. In this paper, we propose a multiobjective genetic framework which integrates the topological and compositional dimensions to uncover community structure in attributed networks. The approach allows to experiment different structural measures to search for densely connected communities, and similarity measures between attributes to obtain high intracommunity feature homogeneity. An efficient and efficacious post-processing local merge procedure enables the generation of high quality solutions, as confirmed by the experimental results on both synthetic and real-world networks, and the comparison with several state-of-the-art methods.

6.
Bioinformatics ; 30(10): 1343-52, 2014 May 15.
Article in English | MEDLINE | ID: mdl-24458952

ABSTRACT

MOTIVATION: Protein-protein interaction (PPI) networks are powerful models to represent the pairwise protein interactions of the organisms. Clustering PPI networks can be useful for isolating groups of interacting proteins that participate in the same biological processes or that perform together specific biological functions. Evolutionary orthologies can be inferred this way, as well as functions and properties of yet uncharacterized proteins. RESULTS: We present an overview of the main state-of-the-art clustering methods that have been applied to PPI networks over the past decade. We distinguish five specific categories of approaches, describe and compare their main features and then focus on one of them, i.e. population-based stochastic search. We provide an experimental evaluation, based on some validation measures widely used in the literature, of techniques in this class, that are as yet less explored than the others. In particular, we study how the capability of Genetic Algorithms (GAs) to extract clusters in PPI networks varies when different topology-based fitness functions are used, and we compare GAs with the main techniques in the other categories. The experimental campaign shows that predictions returned by GAs are often more accurate than those produced by the contestant methods. Interesting issues still remain open about possible generalizations of GAs allowing for cluster overlapping. AVAILABILITY AND IMPLEMENTATION: We point out which methods and tools described here are publicly available. CONTACT: simona.rombo@math.unipa.it SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.


Subject(s)
Algorithms , Protein Interaction Mapping/methods , Proteins/metabolism , Animals , Cluster Analysis , Humans , Proteins/genetics
7.
Evol Comput ; 22(4): 525-57, 2014.
Article in English | MEDLINE | ID: mdl-24256513

ABSTRACT

The paper explores the use of evolutionary techniques in dealing with the image segmentation problem. An image is modeled as a weighted undirected graph, where nodes correspond to pixels, and edges connect similar pixels. A genetic algorithm that uses a fitness function based on an extension of the normalized cut criterion is proposed. The algorithm employs the locus-based representation of individuals, which allows for the partitioning of images without setting the number of segments beforehand. A new concept of nearest neighbor that takes into account not only the spatial location of a pixel, but also the affinity with the other pixels contained in the neighborhood, is also defined. Experimental results show that our approach is able to segment images in a number of regions that conform well to human visual perception. The visual perceptiveness is substantiated by objective evaluation methods based on uniformity of pixels inside a region, and comparison with ground-truth segmentations available for part of the used test images.


Subject(s)
Algorithms , Computing Methodologies , Image Processing, Computer-Assisted/methods , Models, Theoretical , Pattern Recognition, Automated/methods , Visual Perception/physiology , Humans
8.
Article in English | MEDLINE | ID: mdl-22201069

ABSTRACT

Several approaches have been presented in the literature to cluster Protein-Protein Interaction (PPI) networks. They can be grouped in two main categories: those allowing a protein to participate in different clusters and those generating only nonoverlapping clusters. In both cases, a challenging task is to find a suitable compromise between the biological relevance of the results and a comprehensive coverage of the analyzed networks. Indeed, methods returning high accurate results are often able to cover only small parts of the input PPI network, especially when low-characterized networks are considered. We present a coclustering-based technique able to generate both overlapping and nonoverlapping clusters. The density of the clusters to search for can also be set by the user. We tested our method on the two networks of yeast and human, and compared it to other five well-known techniques on the same interaction data sets. The results showed that, for all the examples considered, our approach always reaches a good compromise between accuracy and network coverage. Furthermore, the behavior of our algorithm is not influenced by the structure of the input network, different from all the techniques considered in the comparison, which returned very good results on the yeast network, while on the human network their outcomes are rather poor.


Subject(s)
Cluster Analysis , Protein Interaction Maps , Proteins/chemistry , Proteins/metabolism , Algorithms , Humans , Protein Interaction Mapping/methods
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