1.
Proc Natl Acad Sci U S A
; 120(8): e2219827120, 2023 02 21.
Article
in English
| MEDLINE
| ID: mdl-36791107
ABSTRACT
The discovery of unreported antimicrobial resistance genes (ARGs) remains essential. Here, we report the identification and preliminary characterization of an α/ß-hydrolase that inactivates macrolides. This serine-dependent macrolide esterase co-occurs with emerging ARGs in the environment, animal microbiomes, and pathogens.
