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1.
Medicina (B Aires) ; 49(4): 304-8, 1989.
Article in Spanish | MEDLINE | ID: mdl-2487737

ABSTRACT

The duration of isovolumic relaxation (IR) was used in order to analyze several aspects of diastolic function in patients with dilated cardiomyopathy (DC). This period as measured from the aortic closure sound (A2 on phonocardiogram) to the opening of the mitral valve (on echocardiogram) was determined in 14 patients with DC and compared with findings in 10 normal volunteers (N). Heart rate (HR) and blood pressure (BP) were similar in both groups. The duration of IR was significantly increased in DC (72 ms +/- 6.3 ns) compared with N (41.6 ms +/- 2.8 ns; p less than 0.01). These data suggest that the prolongation in IR may result from alterations in ventricular relaxation.


Subject(s)
Blood Pressure , Cardiomyopathy, Dilated/physiopathology , Heart Rate , Myocardial Contraction , Adult , Aged , Heart Ventricles/physiopathology , Humans , Middle Aged
2.
Medicina (B.Aires) ; 49(4): 304-8, 1989. ilus
Article in Spanish | LILACS | ID: lil-86878

ABSTRACT

A los efectos de analizar algunso aspectos de la función diastólica en la miocardiopatía dilatada (Md) utilizamos la duración del período de relajación isovolúmico (PRI) obtenido por métodos no invasivos en un grupo de pacientes con dicha patología. Se examinaron un total de 24 pacientes, 10 de los cuales configuraron el grupo control (C) y 14 el portador de Md; la duración del PRI se midió desde el comienzo de las vibraciones rápidas del segundo ruido aórtico obtenida por fonocardiograma y hasta el momento de separación de ambas valvas de la mitral analizada por ecocardiograma. Dado que la duración del PRI no sólo depende del estado de la relajación también analizamos otros parámetros como la frecuencia cardíaca y la presión arterial. La cavidad ventricular izquierda estaba significativamente aumentada en los pacientes con Md y la función sistólica estaba severamente deprimida. La frecuencia cardíaca resultó similar en los dos grupos. La presión arterial tampoco resultó diferente. El PRI resultó prolongado significativamente en los pacientes con Md. Los datos analizados permiten concluir que la prolongación del PRI encontrada en los pacientes con Md puede estar vinculada a alteraciones en la relajación miocárdica


Subject(s)
Humans , Adult , Middle Aged , Blood Pressure , Cardiomyopathy, Dilated/physiopathology , Heart Rate , Myocardial Contraction , Heart Ventricles/physiopathology
3.
Medicina [B Aires] ; 49(4): 304-8, 1989.
Article in Spanish | BINACIS | ID: bin-51815

ABSTRACT

The duration of isovolumic relaxation (IR) was used in order to analyze several aspects of diastolic function in patients with dilated cardiomyopathy (DC). This period as measured from the aortic closure sound (A2 on phonocardiogram) to the opening of the mitral valve (on echocardiogram) was determined in 14 patients with DC and compared with findings in 10 normal volunteers (N). Heart rate (HR) and blood pressure (BP) were similar in both groups. The duration of IR was significantly increased in DC (72 ms +/- 6.3 ns) compared with N (41.6 ms +/- 2.8 ns; p less than 0.01). These data suggest that the prolongation in IR may result from alterations in ventricular relaxation.

4.
Medicina [B.Aires] ; 49(4): 304-8, 1989. ilus
Article in Spanish | BINACIS | ID: bin-28071

ABSTRACT

A los efectos de analizar algunso aspectos de la función diastólica en la miocardiopatía dilatada (Md) utilizamos la duración del período de relajación isovolúmico (PRI) obtenido por métodos no invasivos en un grupo de pacientes con dicha patología. Se examinaron un total de 24 pacientes, 10 de los cuales configuraron el grupo control (C) y 14 el portador de Md; la duración del PRI se midió desde el comienzo de las vibraciones rápidas del segundo ruido aórtico obtenida por fonocardiograma y hasta el momento de separación de ambas valvas de la mitral analizada por ecocardiograma. Dado que la duración del PRI no sólo depende del estado de la relajación también analizamos otros parámetros como la frecuencia cardíaca y la presión arterial. La cavidad ventricular izquierda estaba significativamente aumentada en los pacientes con Md y la función sistólica estaba severamente deprimida. La frecuencia cardíaca resultó similar en los dos grupos. La presión arterial tampoco resultó diferente. El PRI resultó prolongado significativamente en los pacientes con Md. Los datos analizados permiten concluir que la prolongación del PRI encontrada en los pacientes con Md puede estar vinculada a alteraciones en la relajación miocárdica (AU)


Subject(s)
Humans , Adult , Middle Aged , Aged , Cardiomyopathy, Dilated/physiopathology , Heart Rate , Blood Pressure , Myocardial Contraction , Heart Ventricles/physiopathology
5.
Clin Cardiol ; 11(5): 329-33, 1988 May.
Article in English | MEDLINE | ID: mdl-3383471

ABSTRACT

Left ventricular (LV) morphological and functional characteristics in 9 women suffering from pregnancy-induced hypertension (PIH) were studied by means of echocardiograms. In order to distinguish which changes depended on the pressure values and which were the result of pregnancy, 10 nonpregnant control women with no heart disease and 10 normal pregnant women (NP) were studied and the results of each of the groups compared. To evaluate the structure, left ventricular systodiastolic diameters and wall thickness were measured. The only statistically significant difference was in the diastolic diameters between the PIH (4.7 +/- 0.3 cm) and the control group (4.4 +/- 0.2 cm) p less than 0.01. Left ventricular mass was significantly increased (p less than 0.01) in the PIH patients (185 +/- 53.1 g) compared to the NP patients (161 +/- 29.6 g) and the control group (125 +/- 17.4 g). No statistically significant differences were found in the radius thickness ratio in the three groups. The systolic function assessed by the shortening percentage was significantly lower (p less than 0.05) in the control group (32.8 +/- 4.4%) and in the NP patients (37.8 +/- 5.2%) than in the PIH group (39 +/- 6.5%). Afterload assessed by isovolumic period stress was significantly greater (p less than 0.01) in the PIH patients (157 +/- 10.6 dyne/cm2) compared with the NP group (118.9 +/- 7.01 dyne/cm2). There were no significant differences between the first group and the control group (134.09 +/- 8.7 dyne/cm2). As evidence of the diastolic function, analysis was made, on the one hand, of diastolic isovolumic period length (DIP).(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Heart/physiopathology , Hypertension/physiopathology , Pregnancy Complications, Cardiovascular/physiopathology , Adolescent , Adult , Blood Pressure , Echocardiography , Female , Heart Rate , Heart Ventricles/pathology , Humans , Hypertension/pathology , Pregnancy , Pregnancy Complications, Cardiovascular/pathology , Systole
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