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Rev Mal Respir ; 37(9): 752-755, 2020 Nov.
Article in French | MEDLINE | ID: mdl-32888731

ABSTRACT

INTRODUCTION: Hypersensitivity pneumonitis (HP) is an interstitial lung disease due to an immunological reaction to exposure, by inhalation, to a large variety of antigens. The patho-physiological mechanism remains poorly understood. The diagnosis can be challenging and requires a detailed medical history taking especially when the clinical presentation is atypical or when the causal agent remains unknown. CASE REPORT: We report the case of a 75-year-old woman with a history of mammary carcinoma who presented with recently identified intramammary adenopathy. Biopsy of the adenopathy revealed non-necrotising, giant cell epithelioid granuloma. A diagnosis of hot tub lung with extra-pulmonary granulomatous lymph node involvement was made based on the clinical, functional, radiological and microbiological investigations. The evolution was favorable following antigen avoidance. CONCLUSION: Extrapulmonary lymph node involvement is rare in HP, suggesting a systemic inflammatory involvement.


Subject(s)
Alveolitis, Extrinsic Allergic/complications , Alveolitis, Extrinsic Allergic/diagnosis , Breast Neoplasms/complications , Carcinoma, Ductal, Breast/complications , Lymphadenopathy/diagnosis , Aged , Breast Neoplasms/diagnosis , Breast Neoplasms/pathology , Carcinoma, Ductal, Breast/diagnosis , Carcinoma, Ductal, Breast/pathology , Diagnosis, Differential , Female , Humans , Lymphadenopathy/complications , Mycobacterium avium Complex/immunology , Mycobacterium avium-intracellulare Infection/complications , Mycobacterium avium-intracellulare Infection/diagnosis
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