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Article in English | MEDLINE | ID: mdl-7976538

ABSTRACT

The purpose of this work was to study CSF dynamics and brain elasticity in patients with peritumoral BE. The investigations was carried out in 14 patients with supratentorial meningiomas. The volume of tumor and the volume of BE was determined planimetrically on CT. CSF dynamics were evaluated using constant-pressure infusion-drainage tests. A significant positive correlation was observed between Ve and F. Definite increases in F in patients with high Ve may depend on the sum of the clearance of BE fluid and the amount of CSF produced. Increase in R correlates with the maximum values of Vt and Ve. This increase in R may depend on the compression of arachnoid villi by tumor and swollen brain.


Subject(s)
Blood-Brain Barrier/physiology , Brain Neoplasms/physiopathology , Cerebrospinal Fluid/physiology , Meningeal Neoplasms/physiopathology , Meningioma/physiopathology , Adult , Cerebral Cortex/blood supply , Cerebrospinal Fluid Pressure/physiology , Female , Humans , Male , Papilledema/physiopathology , Tomography, X-Ray Computed
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