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1.
Sci Robot ; 6(58): eabf1888, 2021 Sep 22.
Article in English | MEDLINE | ID: mdl-34550719

ABSTRACT

During gait neurorehabilitation, many factors influence the quality of gait patterns, particularly the chosen body-weight support (BWS) device. Consequently, robotic BWS devices play a key role in gait rehabilitation of people with neurological disorders. The device transparency, support force vector direction, and attachment to the harness vary widely across existing robotic BWS devices, but the influence of these factors on the production of gait remains unknown. Because this information is key to designing an optimal BWS, we systematically studied these determinants in this work. We report that with a highly transparent device and a conventional harness, healthy participants select a small backward force when asked for optimal BWS conditions. This unexpected finding challenges the view that during human-robot interactions, humans predominantly optimize energy efficiency. Instead, they might seek to increase their feeling of stability and safety. We also demonstrate that the location of the attachment points on the harness strongly affects gait patterns, yet harness attachment is hardly reported in literature. Our results establish principles for the design of BWS devices and personalization of BWS settings for gait neurorehabilitation.


Subject(s)
Man-Machine Systems , Neurological Rehabilitation/methods , Robotics , Biomechanical Phenomena , Body Weight , Calibration , Equipment Design , Female , Gait , Humans , Male , Orthotic Devices , Patient Safety , User-Computer Interface , Walking
2.
Clin Chim Acta ; 62(2): 239-43, 1975 Jul 23.
Article in English | MEDLINE | ID: mdl-1149288

ABSTRACT

Normal subjects were given, on separate occasions, equivalent amounts of glucose, surcrose (""sugar''), and carbohydrates in the form of bread and starch. Neither the glucose, nor the insulin values showed any significant difference in these persons after they had been loaded with the various carbohydrates. The conclusion that can be drawn from this study is that neither the insulin demand nor the secretion rate of insulin are influenced by the type of carbohydrate given. The rate-limiting step, therefore, is the rate of uptake through the intestinal wall, rather than the hydrolysis of the carbohydrate.


Subject(s)
Blood Glucose/metabolism , Carbohydrates/pharmacology , Insulin/blood , Adult , Bread , Dietary Carbohydrates , Fasting , Glucose/pharmacology , Humans , Starch , Sucrose/pharmacology , Time Factors
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