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J Neurovirol ; 22(5): 695-698, 2016 10.
Article in English | MEDLINE | ID: mdl-26942617

ABSTRACT

Neurologic complications related to Epstein-Barr virus (EBV) in immunocompetent adults are rare and most commonly self-limited. However, severe cases have been previously reported in the literature. We describe a case of meningoencephalitis with frontal bilateral hemorrhage in a non-immunocompromised adult following an EBV infection of the central nervous system confirmed by the presence of EBV-DNA in the cerebrospinal fluid. During the patient's hospital stay, there was a favorable clinical and radiologic evolution and the patient was discharged asymptomatic. To our knowledge, this is the fourth case of hemorrhagic meningoencephalitis related to EBV and the first one in an immunocompetent patient with a favorable outcome.


Subject(s)
Acyclovir/therapeutic use , Antiviral Agents/therapeutic use , Cerebral Hemorrhage/drug therapy , Epstein-Barr Virus Infections/drug therapy , Meningoencephalitis/drug therapy , Adrenal Cortex Hormones/therapeutic use , Cerebral Hemorrhage/diagnostic imaging , Cerebral Hemorrhage/immunology , Cerebral Hemorrhage/virology , Epstein-Barr Virus Infections/diagnostic imaging , Epstein-Barr Virus Infections/immunology , Epstein-Barr Virus Infections/virology , Herpesvirus 4, Human/isolation & purification , Humans , Immunocompetence , Magnetic Resonance Imaging , Male , Meningoencephalitis/diagnostic imaging , Meningoencephalitis/immunology , Meningoencephalitis/virology , Middle Aged , Neuroimaging , Treatment Outcome
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