ABSTRACT
Therapy of uncomplicated urinary tract infection (UTI) is based on knowledge of in vitro susceptibility profiles of uropathogens in the geographic region. Microbiological surveillance systems, which lack epidemiological and clinical data to differentiate between complicated and uncomplicated UTI may incorrectly estimate rates of resistance in the community. We determined the susceptibility profile of bacteria isolated from a random sample of 124 adult outpatients with diagnosis of uncomplicated UTI and we compared it with all outpatient urine specimens collected by the same participant laboratories during the same period. Escherichia coli was the most frequently isolated uropathogen in patients with uncomplicated UTI, and its rate of resistance to different antimicrobials was lower than overall resistance rates to E. coli reported by the participating laboratories during the same period. Resistance to cotrimoxazole was significantly lower. These results suggest that surveillance systems without clinical and epidemiological data may incorrectly gauge uropathogen resistance in the community.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Urinary Tract Infections/drug therapy , Adult , Drug Resistance, Bacterial , Humans , Microbial Sensitivity Tests , Prospective Studies , Urinary Tract Infections/microbiologyABSTRACT
The authors report on their experience of 5500 colonoscopies with two cases of perforation of the colon; the rarity and low morbidity and mortality of this complication, related to the experience and the technique of the endoscopist, are discussed. The renal importance of diagnostic and therapeutic colonoscopy is underlined.
