ABSTRACT
The authors present an abridged version of the final report of a State research programme. By introduction of a series of provisions and expedient use of funds available for research it proved possible to reduce the incidence of nosocomial infections in surgical patients from 14% to 12% and in a group with multiple injuries in the surgical intensive care unit from 18% to 10%.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Cross Infection/prevention & control , Intensive Care Units , Multiple Trauma/surgery , Humans , Multiple Trauma/microbiology , PremedicationABSTRACT
Analysis of 100 consecutive cadaverous renal transplants revealed significantly better long-term graft function and patient survival rates and lower incidence of surgical postoperative complications in the second 50 transplants in comparison with the first 50 transplants. The incidence of infectious complications declined with the decrease in the corticosteroids dosage. Severe mycotic infections were prevented by prophylactic administration of antimycotic drugs and by shortening the period of prophylactic antibiotic treatment to 24 hours.
Subject(s)
Infections/etiology , Kidney Transplantation , Postoperative Complications , Adolescent , Adult , Female , Humans , Male , Middle AgedSubject(s)
Carcinoma/surgery , Lung Neoplasms/surgery , Adult , Carcinoma/pathology , Humans , Lung Neoplasms/pathology , Middle AgedABSTRACT
Rupture of an allografted kidney occurred in five patients 5-17 days after transplantation. In one patient the microscopic pathological changes corresponded with the nodose polyarteritis pattern. In four patients interstitial rejection nephritis with severe haemorrhage and haematoma was found. It is suggested that the bleeding is due to peristatic hyperaemia and defects in the inner elastic membranes. In one case multifocal necrotizing arteriopathy was the main pathogenetic factor.