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1.
Clin Ter ; 166(3): e140-5, 2015.
Article in English | MEDLINE | ID: mdl-26152622

ABSTRACT

BACKGROUND AND HYPOTHESIS: There is currently no consensus regarding superiority of the intramedullary fixation over the sliding hip screw. Regional variation remains high and not backed up by solid evidence. Given these premises we aimed to analyze weather implant preference can influence the postoperative survival. Secondary objectives were determining the trend for implant choice and confounding factors associated with intramedullary nails compared to sliding hip screws. PATIENTS AND METHODS: Retrospective data was obtained from patient charts with the main diagnosis of extracapsular/ trochanteric fractures, corresponding to ICD S72.1 codes. Between 2008-2012, 441 patients underwent osteosynthesis with a dynamic hip screw and 155 with intramedullary nail respectively. The living status was determined by comparing the patient identification number against the national population evidence records. RESULTS: The lifetable shows similar survival for both implants over the 5 year period. The yearly mortality was 19.4% for the dynamic hip screw and 21.8% for the intramedullary implant respectively, even though the later were used predominantly in older patients. This age difference is significant according to both parametric and non-parametric tests whereas duration of hospital stay are similar. We found a clear increase in the proportion of intramedullary implants, for a total of 11.2% over the 5 year period. There is no difference for the one year mortality and overall survival between sliding screw plates and intramedullary constructs. CONCLUSIONS: A clear increase in the use of intramedullary implants for trochanteric fractures was observed. This is even more apparent for older ages, presumably due to an higher surgeon confidence with the biomechanical stability of the intramedullary constructs.


Subject(s)
Fracture Fixation, Intramedullary/methods , Hip Fractures/surgery , Bone Nails , Bone Screws , Fracture Fixation, Intramedullary/mortality , Hip Fractures/mortality , Humans , Length of Stay , Retrospective Studies
2.
Eur Rev Med Pharmacol Sci ; 18(19): 2846-50, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25339478

ABSTRACT

Normal healing of fractures is a complex process that relies heavily on a cascade of consecutive activations of immune cells and mediators. This mechanism somewhat overlaps with all processes related to bone metabolism, from the absence of unions to heterotopic ossifications and osteoporosis. We aimed to review and describe this intricate process of bone metabolism with particular focus on abnormal function and to exemplify it with a series of clinical cases which could justify their practical importance. The elbow has great potential for fracture healing but it is very sensitive to prolonged immobilization which can easily lead to intra-articular adherences and stiffness. In addition, the interosseus membrane facilitates communication between the regenerative environments when both radius and ulna are fractured. Such extensive injuries, around the proximal forearm, can lead to heterotopic ossifications and synostosis, which decrease sagittal range of motion through impingement and even block rotational movement through bone bridges. Increased knowledge and awareness of the biological mechanism of fracture healing, will have great improvement in the pharmacological adjuvant treatment of elbow injuries.


Subject(s)
Elbow Injuries , Elbow/physiology , Fracture Healing/physiology , Fractures, Bone/immunology , Fractures, Bone/pathology , Animals , Elbow/pathology , Humans , Osteoporosis/immunology , Osteoporosis/pathology , Range of Motion, Articular/physiology
3.
J Bone Joint Surg Br ; 92(8): 1160-3, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20675765

ABSTRACT

Microfracture is frequently used as the first line of treatment for the repair of traumatic cartilage defects. We present the clinical and histological results 18 months to two-years after treatment in a 26-year-old male with a post-traumatic chondral defect of the medial femoral condyle managed by microfracture covered with chondrotissue, a cell-free cartilage implant made of a resorbable polyglycolic acid felt and hyaluronic acid.


Subject(s)
Cartilage, Articular/injuries , Cartilage, Articular/surgery , Knee Injuries/surgery , Prostheses and Implants , Adult , Arthroplasty, Subchondral , Cartilage, Articular/pathology , Follow-Up Studies , Humans , Hyaluronic Acid , Knee Injuries/pathology , Magnetic Resonance Imaging , Male , Polyglycolic Acid , Polymers , Tissue Scaffolds
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