[Ureteric peristalsis in congenital vesico-ureteral pathology. Integrated sonographic and scintigraphic studies]. / La peristalsi ureterale nella patologia congenita del giunto uretero-vescicale. Studio integrato ecografico e scintigrafico.

Ureteric peristalsis is a key point for urinary progression. Its preoperative evaluation is important to assess indications for surgery. The study of the distal ureter is possible by means of ultrasound. Renal scintigraphy allows for a complete study of urinary progression along the ureter. A combined ultrasound and 99mTc-MAG3 preoperative work-up, has been performed in 32 urinary tracts (16 children ranging in age between 45 days and 11 years). Urinary progression occurs whenever peristaltic contraction makes the ureter lumen unpatent.

Comparative evaluation of three dosages of slow-release isosorbide dinitrate (60, 80, 100 mg) in chronic angina of the aged.

In a single-blind, placebo-controlled study the acute and chronic antianginal effects of three slow-release (SR) new formulations of isosorbide dinitrate (ISDN 60, 80, 100 mg) have been comparatively evaluated in a group of aged affected by chronic stable effort-induced angina. Compared to placebo, overall the active dose paritetically improved the effort tolerance up to 24 h after the first assumption. In the time course of the trial (2 and 4 weeks) the resting hemodynamic changes induced by the first dose were partially blunted without affecting the exercise related-parameters. Also if plasma levels of ISDN and of its metabolites did not correlate to the degree of physical improvement, the peak increase in effort tolerance was observed under 100 mg treatment. Mild to moderate transient headache was experienced by 50% of actively treated and by 20% of placebo treated patients and no other serious adverse effects have been noted. One may conclude that ISDN in slow-release formulations of 60-100 mg isan effective, safe and well tolerated medication in the management of angina in the aged.

[Ischemic heart disease. Value, in the diagnosis, prognosis and selection for therapy, of angiocardioscintigraphy and myocardial scintigraphy]. / Cardiopatia ischemica. Utilità diagnostica, prognostica e nella scelta terapeutica della angiocardioscintigrafia e della scintigrafia miocardica.

Prevailing must be referred to the radioisotopic methods in the diagnosis of the ischemic heart disease. Alterations of coronary artery disease with first pass and multiple gated equilibrium cardiac blood pool scintigraphy and myocardial scintigraphy are described. The importance of such data--particularly if obtained under stress--are noticed and also its usefulness at the prognostic aims, for the decision between medical or surgical therapy.