[Relief of visual fatigue in visual strain-related work]. / Sniatie zritel'nogo utomleniia pri zritel'no-napriazhennykh rabotakh.

Work associated with visual strain results in visual fatigue. Laser radiation in red part of spectrum relieves visual fatigue, activating reduction-oxidation thiol disulfide system in eyes.

[Myocardial cytoprotection with trimetazidine in patients with ischemic heart disease during surgical stress]. / Miokardial'naia tsitoprotektsiia s pomoshch'iu trimetazidina u bol'nykh s ishemicheskoi bolezn'iu serdtsa pri operatsionnom stresse.

Fluctuations of the thiol disulfide system were shown to be interrelated with changes in the ECG indices. Trimetazidine since it has antioxidant properties was found to be effective in patients with low thiol disulfide ratios. A single dose of 0.8 mg/kg of the body mass was shown to inhibit the appearance of stress-dependent ischemic symptoms during surgical procedures.

[The dynamic indices of the thiol-disulfide system and of the electrocardiogram under conditions of surgical stress]. / Dinamika pokazatelei tioldisul'fidnoi sistemy i élektrokardiogrammy v usloviiakh operatsionnogo stressa.

Changes of the thiol-disulfide balance and electrocardiographic indices were studied in ischemic heart disease patients undergoing operation stress. It was shown that the operative procedure resulted in a shift of the redox state to oxidation in the thiol-disulfide system, especially in its protein part. The revealed correlation between the value of the thiol-disulfide ratio and ECG changes attest to the significance of the state of the blood thiol-disulfide system for the assessment of the degree of ischemic alterations in the myocardium.

[The role of antioxidant mechanisms in body's reactions to the effects of low-intensity laser irradiation]. / Rol' antioksidantnykh mekhanizmov v reaktsiiakh organizma na deistvie nizkointensivnogo lazernogo izlucheniia.

Some mechanisms of general and local effects of laser radiation with various wavelength were considered. Both stimulating and stress effects of low-intensive laser radiation realized via antioxidant and free-radical pathways were shown. It was found that the level of SH and SS-groups in tissues and blood is the most sensitive index of laser effect. Measurements of SH and SS-groups concentration are recommended as criterion of harmless laser use in clinics.

[Maximum permissible level of disseminated laser radiation with the wave length of 0.44 mkm]. / Predelno dopustimyi uroven rasseiannogo lazernogo izlucheniia s dlinoi volny v 0.44 mkm.

There where investigated the local and general reactions of 48 male rabbits (chinchilla) exposed to diffused laser radiation with wavelength of 0.44 microns. In the experiments 120 days period of exposure followed by 30 days period of rest. The maximal permissible level for laser radiation was established.

[Difficulties in the diagnosis of rheumatic heart defects in elderly patients]. / Trudnosti raspoznavaniia revmaticheskikh porokov serdtsa u bol'nykh pozhilogo vozrasta.

Clinical and autopsy data presented in this paper illustrate difficulties arising in diagnosis of rheumatic heart disease (RHD) in elderly patients. RHD misdiagnosis is explained by unclear clinical symptoms, undone laboratory tests, concomitant diseases, misinterpretation of some objective indications (auscultatory symptoms, ECG). To diagnose acquired RHD earlier the physicians are recommended to refer their patients to ultrasound investigations of the heart.

[Permissible level of laser radiation of wavelength 10.6 microns]. / Predel'no dopustimyi uroven' lazernogo izlucheniia dlinoiu volny 10,6 mkm.

In a four-month experiment with 102 male rabbits and 42 HRS/U mice and 30 days after termination thereof, study was made of local and general response of an organism to the effect of laser radiation (10.6 microns wave length and energy exposition 1/7 of the threshold). The radiation tolerance level was estimated.

[The stimulating effect of helium-neon laser radiation on rabbit eyes]. / O stimuliruiushchem éffekte deistviia izlucheniia gelii-neonovogo lazera na glaza krolika.

Local and general reactions have been studied after subjecting a rabbit eye to dispersed helium-neon laser radiation, 8 x 10(-6) wt/cm-2, 10 min daily for 10 days. There were recorded increase of blood filling of the uveal tract of the eye, changes in the indices of systemic hemodynamics, systolic and diastolic pressure, stroke and minute volume of blood volume, activation of separate links of antioxidant system connected both with oxidation-reduction of thiol disulfide system and the functioning of antiperoxide enzymes. The activation of antioxidant system has a local character, the changes in the retina of the eye and pigmented epithelium is expressed stronger than in the peripheral blood. The results obtained speak about relationship between the stimulating effect of helium-neon laser radiation on the rabbit eye and activation of antioxidant system.

[Sensitivity of animals to CO2 laser radiation]. / Chuvstvite'lnos't organizma zhivotnykh k izlucheniiu CO2-lazera.

The study was undertaken to analyze the state of visual, cardiovascular and antioxidant systems along with peripheral blood exposed to laser emission with the wavelength of 10.6 mm and energetic exposure equal to that of threshold (21 J.cm2) and subthreshold (1/7 of the threshold value). Not only local but also general changes were detected. The cardiovascular and antioxidant systems were most sensitive to this type of exposure. The degree of changes was dose-dependent.

[Hemodynamic characteristics in different models of experimental hypokinesia]. / Osobennosti gemodinamiki pri razlichnyh modeliakh éksperimental'noi gipokinezii.

The effect of hypokinesia on systemic hemodynamics has been investigated in rat and rabbit experiments using dispersion analysis. It has been shown that different models of hypokinesia produce hemodynamic disorders which depend on the type and duration of hypokinesia and animal responses to them. In rats the exposure to hypokinesia causes the hypertensive symptom-complex while in rabbits hypotensive disorders. The application of the dispersion analysis allows quantitative estimation of the hypokinetic effect on demonstrative indexes and detection of the most vulnerable parameter.