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1.
Wiad Lek ; 42(4): 205-9, 1989 Feb 15.
Article in Polish | MEDLINE | ID: mdl-2576167

ABSTRACT

The results of pharmacological treatment are presented in a group of 60 patients with exacerbation of coronary disease. The patients were divided into two subgroups: subgroup 1 of 26 patients with intensification of angina of effort, subgroup II of 34 patients with unstable angina. Combined pharmacological treatment was given: nitrates, B-adrenolytic drugs and nifedipine (Cordipin, Krka) Addition of Cordipin produced clinical and electrocardiographic improvement in 44 cases (73%): all patients in subgroup I and 18 (53%) in subgroup II. Cordipin was well tolerated, and produced no serious side effects.


Subject(s)
Coronary Disease/drug therapy , Nifedipine/administration & dosage , Adrenergic beta-Antagonists/administration & dosage , Adult , Aged , Clinical Trials as Topic , Coronary Disease/physiopathology , Drug Therapy, Combination , Female , Hemodynamics/drug effects , Hemodynamics/physiology , Humans , Male , Middle Aged , Nitrates/administration & dosage
2.
Kardiol Pol ; 32(5): 248-54, 1989.
Article in Polish | MEDLINE | ID: mdl-2635237

ABSTRACT

In 41 patients with cardiac defects cardiac catheterization and echocardiographic examination were performed to evaluate the usefulness of Doppler echocardiography for estimation the grade of pulmonary hypertension. Parameter for noninvasive estimation of mean pulmonary artery pressure was the acceleration time (AcT) calculated basing on pulsed Doppler recordings of blood flow through the right ventricular outflow tract. Technics of examination and calculation of mean pulmonary artery pressure (MPAP) were concordant with Kitabatake's methodology. Patients were divided into 3 groups according to MPAP values measured by the invasive method. MPAP values obtained using Doppler method were not identical with results of direct measurements, but in the majority of patients (85%) Doppler method allowed to properly qualify patients to a respective group--with normal, moderate or very high pulmonary artery pressure. We think that the presented method is a semiquantitative one and useful for monitoring of pulmonary pressure in patients with cardiac defects.


Subject(s)
Hypertension, Pulmonary/diagnosis , Pulmonary Artery/physiopathology , Pulmonary Circulation/physiology , Adult , Aged , Blood Flow Velocity/physiology , Echocardiography, Doppler , Female , Humans , Hypertension, Pulmonary/physiopathology , Male , Middle Aged
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