Subject(s)
Pharyngitis/drug therapy , Administration, Inhalation , Adult , Aged , Bacterial Infections/drug therapy , Bacterial Infections/microbiology , Bacterial Infections/pathology , Depsipeptides , Female , Fusarium , Humans , Male , Middle Aged , Mouth Mucosa/drug effects , Pharyngitis/microbiology , Pharyngitis/pathology , Severity of Illness IndexSubject(s)
Phytotherapy/methods , Plant Preparations/administration & dosage , Rhinitis/drug therapy , Sinusitis/drug therapy , Administration, Intranasal , Adolescent , Adult , Chronic Disease , Drug Combinations , Follow-Up Studies , Humans , Middle Aged , Rhinitis/complications , Sinusitis/complications , Treatment OutcomeABSTRACT
A pilot morphological (radioautographic) study of healthy and affected palatine tonsils (in hypertrophy and toxic-allergic form of chronic tonsillitis) in children and adults has shown that intensity of biosynthetic processes (protein-synthetic -- RNA synthesis and proliferative activity -- DNA synthesis) in the cells of palatine tonsils and structural changes of their tissues depend on characteristics of pathological process. Microbial penetration into the tonsils with formation of an active focus of chronic infection is traced.
Subject(s)
Palatine Tonsil/pathology , Tonsillitis/pathology , Adolescent , Adult , Autoradiography , Cell Proliferation , Child , Child, Preschool , Chronic Disease , Humans , Middle Aged , Palatine Tonsil/metabolism , Proteins/genetics , Proteins/metabolism , RNA/metabolism , Tonsillitis/metabolismSubject(s)
Adjuvants, Immunologic/therapeutic use , Anti-Bacterial Agents/adverse effects , Anti-Bacterial Agents/therapeutic use , Antigens, Bacterial/therapeutic use , Antigens, Fungal/therapeutic use , Otolaryngology/methods , Respiratory Tract Infections/drug therapy , Sinusitis/drug therapy , Thimerosal/therapeutic use , Adjuvants, Immunologic/administration & dosage , Aerosols , Anti-Bacterial Agents/administration & dosage , Antigens, Bacterial/administration & dosage , Antigens, Fungal/administration & dosage , Bacteria , Drug Administration Schedule , Drug Combinations , Humans , Immunosuppression Therapy , Organic Chemicals , Thimerosal/administration & dosageSubject(s)
Cochlear Diseases/drug therapy , Vestibular Diseases/drug therapy , Adult , Age Factors , Betahistine/administration & dosage , Betahistine/therapeutic use , Cochlear Diseases/diagnosis , Cochlear Diseases/etiology , Cochlear Diseases/physiopathology , Female , Ginkgo biloba , Hemodynamics , Humans , Male , Middle Aged , Naphazoline/administration & dosage , Naphazoline/therapeutic use , Pentoxifylline/administration & dosage , Pentoxifylline/therapeutic use , Phytotherapy , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use , Sex Factors , Time Factors , Vasodilator Agents/administration & dosage , Vasodilator Agents/therapeutic use , Vestibular Diseases/diagnosis , Vestibular Diseases/etiology , Vestibular Diseases/physiopathologySubject(s)
Chlamydia Infections/complications , Mycoplasma Infections/complications , Respiratory Tract Infections/microbiology , Chlamydia Infections/immunology , Humans , Immunoglobulin A/immunology , Immunoglobulin G/immunology , Immunoglobulin M/immunology , Mycoplasma Infections/immunology , Respiratory Tract Infections/immunologyABSTRACT
A dynamic 4-year monitoring of aerobic bacterial environment in the ENT department shows its relative qualitative stability with predominance of the coccal flora, primarily staphylococcal. Gram-negative flora was represented for the most part with non-fermentating microorganisms, most of them Acinetobacter. A wide-spectrum resistance to antibacterial drugs was found. This resistance has a trend to extend.
Subject(s)
Anti-Bacterial Agents/pharmacokinetics , Anti-Bacterial Agents/therapeutic use , Drug Resistance, Bacterial , Respiratory Tract Infections/drug therapy , Respiratory Tract Infections/microbiology , Anti-Bacterial Agents/classification , HumansABSTRACT
The authors present pilot experience with transcranial duplex scanning (TCDS) of the cerebral vessels in 17 patients with secondary cochleovestibular neuritis combined with chronic leptomeningitis (primarily of the posterior cranial fossa). This method has determined extra- and intracranial hemodynamics, characterized arterial and venous blood flow qualitatively and quantitatively, outlined possible genetically determined factors in development of dyscirculatory disorders. Finally, hemodynamic defects of two types were revealed in 12 patients. Type 1 (3 patients) was characterized by asymmetric circulation in the territory of the middle, anterior and posterior cerebral arteries, by the absence of venous congestion. Type 2 (9 patients) was characterized by impaired venous outflow manifesting as higher speed of the blood flow and its phase response along the intracranial veins and sinuses. In 7 patients these defects combined with asymmetric circulation along brain stem arteries. These patients were diagnosed to have perilymphatic labyrinthine hydrops.
Subject(s)
Brain/blood supply , Brain/diagnostic imaging , Cochlear Nerve , Meningitis/complications , Neuritis , Tomography, Emission-Computed/methods , Adult , Chronic Disease , Cochlear Nerve/blood supply , Cochlear Nerve/diagnostic imaging , Cochlear Nerve/physiopathology , Endolymphatic Hydrops/diagnosis , Female , Hemodynamics/physiology , Humans , Male , Middle Aged , Neuritis/diagnosis , Neuritis/etiology , Neuritis/physiopathology , Pilot Projects , Vestibular Nerve/blood supply , Vestibular Nerve/diagnostic imaging , Vestibular Nerve/physiopathologySubject(s)
Adjuvants, Immunologic/therapeutic use , Ear Diseases/drug therapy , Laryngeal Diseases/drug therapy , Otolaryngology , Pharyngeal Diseases/drug therapy , Adjuvants, Immunologic/administration & dosage , Administration, Inhalation , Adolescent , Adult , Bacteria , Drug Administration Schedule , Female , Humans , Male , Middle AgedABSTRACT
The article is a brief review of clinical and topographic anatomy of the palatine tonsils. Their role in formation of general and local immunity is shown. Etiological and pathogenetic aspects of chronic tonsillitis are considered: most frequent causing agents, underlying pathogenetic and immunological mechanisms. B.S. Preobrazhensky's and V.T. Palchun's clinical classification of chronic tonsillitis is presented. New approaches to etiopathogenetic treatment of chronic tonsillitis are described.
Subject(s)
Tonsillitis/diagnosis , Tonsillitis/therapy , Chronic Disease , Humans , Tonsillitis/classificationABSTRACT
Aerobic microbes in ENT departments were studied. The following strains were isolated: Staphylococcus, Streptococcus, Enterococcus, Acinetobacter, Klebsiella, Pseudomonas, Flavobacter, Citrobacter, Enterobacter, Escherichia, Aspergillus, Candida. 54.5% of the isolated strains were of hospital origin. Comparative evaluation of antibiotic resistance has shown a wide spectrum of resistance of the isolated microorganisms to antimicrobial drugs, among those to the drugs used in the ENT departments.
Subject(s)
Anti-Bacterial Agents/pharmacology , Bacteria, Aerobic/drug effects , Bacteria, Aerobic/isolation & purification , Otolaryngology , Humans , Sensitivity and SpecificityABSTRACT
20-year experience with 220 cases of cochleovestibular disorders treated with betaserk shows high efficacy of this drug in the above patients, especially at initial stages of Meniere's disease. Betaserk is recommended for wide outpatient practice.
Subject(s)
Betahistine/therapeutic use , Cochlear Diseases/drug therapy , Histamine Agonists/therapeutic use , Vestibular Diseases/drug therapy , Aged , Humans , Meniere Disease/drug therapyABSTRACT
Efficacy of local treatment with ligenten which was introduced after irrigation of the nasal sinuses was tried versus control intranasal introduction of 1% dioxidin solution. 35 and 25 patients with acute sinusitis or aggravation of chronic purulent sinusitis were treated, respectively. Subjective and objective responses in the study and control groups assessed with the use of sensor-analogue and visual-analogue scale demonstrated higher efficacy of ligenten.
Subject(s)
Anti-Infective Agents/therapeutic use , Gels/therapeutic use , Gentamicins/therapeutic use , Lidocaine/therapeutic use , Quaternary Ammonium Compounds/therapeutic use , Sinusitis/drug therapy , Administration, Topical , Adult , Anti-Infective Agents/administration & dosage , Drug Combinations , Female , Gels/administration & dosage , Gentamicins/administration & dosage , Humans , Lidocaine/administration & dosage , Male , Middle Aged , Quaternary Ammonium Compounds/administration & dosage , Sinusitis/etiology , Treatment OutcomeSubject(s)
Otitis Media , Acute Disease , Ear, Middle/microbiology , Ear, Middle/pathology , Ear, Middle/surgery , Haemophilus influenzae/isolation & purification , Humans , Moraxella catarrhalis/isolation & purification , Otitis Media/microbiology , Otitis Media/pathology , Otitis Media/surgery , Oxygen/blood , Severity of Illness Index , Streptococcus pneumoniae/isolation & purificationABSTRACT
Clinical and microbiological findings led the authors to the conclusion that antibacterial drugs rovamycin and amox-clav are active against ENT infection and inflammation. The trial included 69 and 42 patients given rovamycin and amox-clav, respectively.
Subject(s)
Bacterial Infections/drug therapy , Drug Therapy, Combination/therapeutic use , Otorhinolaryngologic Diseases/drug therapy , Spiramycin/therapeutic use , Adolescent , Adult , Aged , Amoxicillin/administration & dosage , Amoxicillin/therapeutic use , Amoxicillin-Potassium Clavulanate Combination , Bacteria/isolation & purification , Clavulanic Acids/administration & dosage , Clavulanic Acids/therapeutic use , Drug Therapy, Combination/administration & dosage , Female , Humans , Inflammation , Male , Middle Aged , Otorhinolaryngologic Diseases/microbiology , Spiramycin/administration & dosage , Time FactorsABSTRACT
The response to lomuzol was registered in 37 out of 39 patients with allergic rhinitis given lomuzol. In 16 patients the response was complete, in 14 partial, in 7 satisfactory. In 6 patients of placebo no effect was recorded. The drug proved uneffective in hypertrophy of the turbinate bones.