[Level of lipid peroxides and activity of antioxidant system enzymes in pulmonary tissue of rats with acute pneumonia]. / Vmist produktiv perekysnoho okysnennia lipidiv i aktyvnist' fermentiv antyokysniuval'noï systemy u lehenevii tkanyni shchuriv pry hostrii pnevmoniï.

The model process of acute pneumonia in rats, after 2 hours after intranasal infectioning by Staphylococcus aureus culture, is accompanied with DK and MDA level growth, and SOD and catalase activity increase in pulmonary tissue of males and females. Later, after 6 hours after contamination the growth of POL products content was observed, the SOD and catalase activity in lungs is lowered. At the same time, in females the PLO indexes and SOD activity continue to grow. This suggests that females have more AOS enzymatic reserves than males.

[State of lipid peroxidation and blood antioxidant system in rats with acute pneumonia]. / Stan perekysnoho okysnennia lipidiv ta aktyvnist' antyokysniuval'noï systemy u krovi shchuriv pry hostrii pnevmoniï.

The functional condition of prooxidant--antioxidant system in rat blood plasma in acute pneumonia, on the 4th full day after intranasal animals' infectioning, by Staphylococcus Aureus culture depending on sex was studied. The investigation of PLO indexes and AOS activity on the 4th full-day after animals' contamination with St. aureus culture, in blood plasma, in acute pneumonia, showed the increase of DK and MDA content, and oppression of AOS-SOD ferments and catalase activity. In males these changes were more expressed indicating an exhaustion of functional reserves of antioxidant system.