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1.
Rev Esp Anestesiol Reanim ; 61(2): 109-11, 2014 Feb.
Article in Spanish | MEDLINE | ID: mdl-23276378

ABSTRACT

Hepatotoxicity is a rare complication following the use of propofol and can be potentially serious if an early diagnosis is not made. Propofol is being increasingly used in daily practice, not only in surgery, but also in outpatient sedation procedures, such as endoscopy. Acarbose is a well-known drug used in type 2 diabetes treatment, particularly in the early phase. A case is reported on a patient who suffered an acute hepatitis secondary to the use of propofol in ophthalmology surgery, a hepatitis probably enhanced by prior use of acarbose, a drug that also can cause hepatotoxicity. An early diagnosis and it was resolved without complications. This case could contribute to improve pre-anesthetic evaluation of patients who will be undergoing sedation with propofol in order to avoid the possible appearance of hepatitis.


Subject(s)
Acarbose/adverse effects , Anesthetics, Intravenous/adverse effects , Chemical and Drug Induced Liver Injury/etiology , Hypoglycemic Agents/adverse effects , Propofol/adverse effects , Acarbose/pharmacokinetics , Acarbose/therapeutic use , Aged , Anesthesia, Intravenous , Anesthetics, Intravenous/pharmacokinetics , Diabetes Mellitus, Type 2/drug therapy , Drug Interactions , Female , Humans , Hypoglycemic Agents/pharmacokinetics , Hypoglycemic Agents/therapeutic use , Lens Implantation, Intraocular , Phacoemulsification , Propofol/pharmacokinetics , Time Factors
2.
Medicine (Madr) ; 11(53): 3165-3170, 2014 Apr.
Article in Spanish | MEDLINE | ID: mdl-32287898

ABSTRACT

Imported parasitoses are an uncommon condition in our setting, although recently, the increase of migratory flow has been leading to an increase in the detected cases of these diseases. This fundamentally occurs in immigrants from tropical zones where these conditions are generally endemic. However, imported parasitoses are being increasingly diagnosed in Western persons who have lived in the tropics for different reasons. When examining a subject with cardiovascular syndromes with a possible parasitic origin, it could be useful to classify the possible geographic zone of origin in order to perform disease screening. Then, if the problem is mainly respiratory, it would be well to first rule out the existence of tuberculosis in the case of long stays and to individual the diagnosis according to the geographic area, season of the year, type of exposure and symptoms presented, in the case of shorter stays.

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