ABSTRACT
La hepatotoxicidad es una complicación infrecuente tras el empleo de propofol, que puede ser potencialmente grave en caso de no realizarse un diagnóstico precoz. El propofol es un fármaco cada vez más empleado en la práctica diaria no solo en cirugía sino también en la sedación de procedimientos invasivos ambulatorios tales como la endoscopia. Acarbosa es un fármaco clásico en el tratamiento de la diabetes tipo 2 en estadios iniciales que puede causar de forma infrecuente hepatitis tóxica. Se presenta el caso de una paciente que sufrió una hepatitis aguda secundaria al empleo de propofol como anestesia oftalmológica, hepatitis probablemente potenciada por el uso previo de acarbosa. El cuadro se diagnosticó de forma precoz y se resolvió sin complicaciones. El conocimiento de esta complicación en el ámbito de la anestesiología se revela cada vez más importante para mejorar la valoración preanestésica de los pacientes que vayan a ser sedados con propofol y así evitar en lo posible su aparición (AU)
Hepatotoxicity is a rare complication following the use of propofol and can be potentially serious if an early diagnosis is not made. Propofol is being increasingly used in daily practice, not only in surgery, but also in outpatient sedation procedures, such as endoscopy. Acarbose is a well-known drug used in type 2 diabetes treatment, particularly in the early phase. A case is reported on a patient who suffered an acute hepatitis secondary to the use of propofol in ophthalmology surgery, a hepatitis probably enhanced by prior use of acarbose, a drug that also can cause hepatotoxicity. An early diagnosis and it was resolved without complications. This case could contribute to improve pre-anesthetic evaluation of patients who will be undergoing sedation with propofol in order to avoid the possible appearance of hepatitis (AU)
Subject(s)
Humans , Female , Adult , Acarbose/administration & dosage , Acarbose/adverse effects , Acarbose/pharmacokinetics , Propofol/administration & dosage , Propofol/adverse effects , Propofol/pharmacology , /complications , /diagnosis , Hepatitis/complications , Anesthesia/methods , Acarbose/metabolism , Hepatitis/drug therapy , Acarbose/toxicity , Anesthesia/standards , Propofol/pharmacokinetics , Propofol/therapeutic use , Early Diagnosis , Anesthesiology/ethics , Anesthesiology/methods , Anesthesiology/standardsABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Guillain-Barre Syndrome/complications , Lymphoma, Non-Hodgkin/diagnosis , Paralysis/etiology , Functional NeuroimagingSubject(s)
Humans , Male , Female , /epidemiology , /prevention & control , Chagas Disease/epidemiology , Chagas Disease/prevention & control , Infectious Disease Transmission, Vertical/prevention & control , Infectious Disease Transmission, Vertical/statistics & numerical data , Sensitivity and Specificity , Enzyme-Linked Immunosorbent Assay/methods , Enzyme-Linked Immunosorbent Assay , Trypanosoma cruzi , Trypanosoma cruzi/isolation & purificationSubject(s)
Humans , Male , Female , Middle Aged , Lipid Metabolism , Lipid Metabolism/physiology , Lipid Metabolism Disorders/drug therapy , Lipid Metabolism Disorders/prevention & control , /therapeutic use , Lovastatin/therapeutic use , Cholesterol, LDL/analysis , Cholesterol, LDL , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/prevention & control , Bias , /analysis , /poisoningABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Thrombosis/complications , Thrombosis/diagnosis , Pulmonary Embolism/complications , Hypertension/complications , Pacemaker, Artificial/adverse effects , Pacemaker, Artificial , Radiography, Thoracic/methods , Enoxaparin/therapeutic use , Acenocoumarol/therapeutic use , Risk Factors , Embolism/complications , Dyspnea/complications , Cardiomegaly/complications , Pulmonary EmbolismABSTRACT
No disponible
Subject(s)
Humans , Pericarditis/complications , Polyendocrinopathies, Autoimmune/complications , Acute DiseaseABSTRACT
No disponible
Subject(s)
Aged , Aged, 80 and over , Humans , Bone Neoplasms/diagnosis , Prostatic Neoplasms/diagnosis , Fatal Outcome , Hypercalcemia/etiology , Coma/etiology , Bone Neoplasms/secondary , Prostatic Neoplasms/pathologyABSTRACT
No disponible
Subject(s)
Female , Aged , Humans , Actinomycosis/diagnosis , Bile Duct Diseases/diagnosis , Actinomycosis/therapy , Bile Duct Diseases/therapyABSTRACT
No disponible
Subject(s)
Male , Humans , Antithrombin III Deficiency/diagnosis , Venous Thrombosis/complications , Lung Neoplasms/complicationsABSTRACT
No disponible
Subject(s)
Middle Aged , Female , Humans , Thyroxine , Hydroxymethylglutaryl-CoA Reductase Inhibitors , Rhabdomyolysis , Hypercholesterolemia , HypothyroidismABSTRACT
No disponible
Subject(s)
Aged , Male , Humans , Citrobacter freundii , Bacteremia , Enterobacteriaceae InfectionsABSTRACT
No disponible
