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1.
Zh Nevrol Psikhiatr Im S S Korsakova ; 121(11. Vyp. 2): 95-102, 2021.
Article in Russian | MEDLINE | ID: mdl-35038853

ABSTRACT

OBJECTIVE: Study of clinical and psychophysiological disorders in preschool children with anxiety disorders and assessment of the effectiveness of Anvifen in the treatment of this pathology. MATERIAL AND METHODS: The study included 64 children aged 5 to 7 years with a diagnosis of phobic disorder of childhood (F93.1). Clinical, pathophysiological and psychometric research methods were used in the work. Anvifen was used to treat 40 patients from the study group. Patient satisfaction with treatment outcomes was assessed using the Integrative Medicine Patient Satisfaction Scale (IMPSS). RESULTS: According to the data obtained, in the study group, 76.5% of patients had fear associated with health (infections, illness, death); in 68.6% of cases - fears of the death of parents; in 57.5% of cases - fear of the dark; in 40.6% of cases - fears of loneliness; in 31.2% of cases - fears related to the educational institution; in 28.1% - fear of animals, as well as a lower level of emotional identification and a significantly higher level of impulsivity than in the control group. Sleep disorders were recorded in 87.5% of children from the study group. After the course of treatment, an improvement in the condition was noted in 70.0% of children in the form of a decrease in anxiety, impulsivity and an improvement in falling asleep and a decrease in the number of awakenings. CONCLUSION: The use of Anvifen leads to a significant improvement in the quality of sleep and a decrease in signs of anxiety before sleep and signs of impaired quality of wakefulness, which allows us to conclude that Anvifen is effective in treating anxiety disorders in children.


Subject(s)
Emotional Regulation , Phobic Disorders , Anxiety , Anxiety Disorders/drug therapy , Humans
2.
Article in Russian | MEDLINE | ID: mdl-27635617

ABSTRACT

AIM: To study the efficacy of pantogam syrup 10% (hopantenic acid) in the treatment of breath-holding spells (BHS). MATERIAL AND METHODS: Sixty children, aged from 2 to 4 years, with BHS were studied. The evaluation of clinical manifestations and anxiety level was performed. Results of neurophysiological examination (long-term video-EEG-monitoring) were analyzed. Children were divided into 2 groups: main, in which the patients received pantogam syrup, and control group, in which only psychological methods were used. RESULTS AND CONCLUSION: The results of the clinical and neurophysiological studies performed after the treatment, showed the clinical improvement in 73.3% of patients of the main group compared with similar data from the children in the control group (16.7%). The anxiety level significantly decreased after the neuroprotective therapy. A comparative analysis of electroencephalographic indicators demonstrated a significant (р<0.05) reduction in the power range of slow rhythms and manifestations of functional immaturity of the brain in patients of the main group. These results give evidence for the high efficacy of pantogam syrup in the treatment of children with BHS.


Subject(s)
Anxiety/complications , Anxiety/drug therapy , Apnea/drug therapy , Apnea/psychology , Pantothenic Acid/analogs & derivatives , gamma-Aminobutyric Acid/analogs & derivatives , Breath Holding , Child, Preschool , Electroencephalography , Female , Humans , Male , Pantothenic Acid/administration & dosage , gamma-Aminobutyric Acid/administration & dosage
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