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Ross Fiziol Zh Im I M Sechenova ; 84(3): 233-7, 1998 Mar.
Article in Russian | MEDLINE | ID: mdl-9742597

ABSTRACT

Picrotoxin-induced kindling was shown to suppress the blastogenic response to bacterial lipopolysaccharide and phytogemagglutinin in male Wistar rats. The delta-sleep-inducing peptide as well as carbamazepine prevented the epileptogenic effects of picrotoxin. Carbamazepine was also effective against decreasing of phytogemagglutinin-induced blastogenic response.


Subject(s)
Convulsants/toxicity , Epilepsy/pathology , Kindling, Neurologic , Lymphocyte Activation , Picrotoxin/toxicity , Animals , Anticonvulsants/pharmacology , Carbamazepine/pharmacology , Delta Sleep-Inducing Peptide/pharmacology , Epilepsy/immunology , Lipopolysaccharides/toxicity , Lymphocyte Activation/immunology , Male , Phytohemagglutinins/immunology , Rats , Rats, Wistar
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