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Xpitx3: a member of the Rieg/Pitx gene family expressed during pituitary and lens formation in Xenopus laevis.

Pommereit, D; Pieler, T; Hollemann, T.

Mech Dev ; 102(1-2): 255-7, 2001 Apr.

Article in English | MEDLINE | ID: mdl-11287205

ABSTRACT

Xpitx3 is the Xenopus homologue of the mouse Pitx3 gene and belongs to the family of RIEG/PITX homeobox genes. Here, we report on the embryonic expression of Xpitx3. It is transcribed in the presumptive pituitary already at the open neural tube stage. During further development Xpitx3 is strongly transcribed in the pituitary Anlage, the lens placodes and head mesenchyme, respectively.

Subject(s)

Homeodomain Proteins/biosynthesis , Homeodomain Proteins/genetics , Lens, Crystalline/embryology , Nuclear Proteins , Pituitary Gland/embryology , Transcription Factors/biosynthesis , Transcription Factors/genetics , Xenopus laevis/embryology , Amino Acid Sequence , Animals , Cloning, Molecular , DNA, Complementary/metabolism , Humans , In Situ Hybridization , Mice , Molecular Sequence Data , Multigene Family , Mutation , Paired Box Transcription Factors , Promoter Regions, Genetic , Rats , Reverse Transcriptase Polymerase Chain Reaction , Sequence Homology, Amino Acid , Tissue Distribution , Homeobox Protein PITX2

ABSTRACT

Subject(s)

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