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1.
Arch Mal Coeur Vaiss ; 86(12): 1769-71, 1993 Dec.
Article in French | MEDLINE | ID: mdl-8024380

ABSTRACT

The authors report the case of a 32 year old woman with no risk factors for thromboembolism apart from a raised Lipoprotein (a) level, in whom a mobile thrombus of the ascending aorta was diagnosed only by transoesophageal echocardiography after multiple episodes of systemic embolism. After surgical excision the thrombus recurred and death ensued on the 17th postoperative day after multiple visceral embolism despite adequate anticoagulant therapy. This is a rare condition, the outcome of which seems often to be fatal, due to early recurrence irrespective of the treatment (anticoagulant or platelet antiaggregant therapy). This case illustrates the value of systematic transoesophageal echocardiography for the investigation of cerebral or peripheral ischaemic episodes without carotid artery disease and raises the problem of the best way of treating this pathology.


Subject(s)
Aortic Diseases/diagnostic imaging , Echocardiography, Transesophageal , Thrombosis/diagnostic imaging , Adult , Aortic Diseases/complications , Aortic Diseases/surgery , Brain Ischemia/etiology , Fatal Outcome , Female , Humans , Lipoprotein(a)/blood , Recurrence , Thrombosis/complications , Thrombosis/surgery
2.
Ann Cardiol Angeiol (Paris) ; 42(7): 339-44, 1993 Sep.
Article in French | MEDLINE | ID: mdl-8285561

ABSTRACT

The reliability and safety of Doppler echocardiography with dipyridamole (0.84 mg/kg in 10 min) were evaluated in 63 patients an average of 7 days after a thrombolysed early lateral infarct and 24 hours before follow-up coronary arteriography. The aims of the test were the detection of tight stenoses (diameter reduced by more than 75%) affecting the artery responsible for the infarct as well as the other coronary vessels, using the vasodilator action of dipyridamole. The echocardiographic manifestation of induced coronary steal consisted of transitory asynergism in the territory of the artery involved. Clinical tolerability of the test was good. The brief onset of anginal pain was nevertheless seen in 6 patients. Analysis of the zone corresponding to the necrosed area was possible in only 43 cases. Sensitivity of the test for detection of a post-infarction residual stenosis was 64% (39-89) and specificity 90% (79-100). Study of other territories was possible in 59 cases. Sensitivity of the test for the diagnosis of multiple vessel disease was 70% (42-98) and specificity 94% (88-100). In the population as a whole, Doppler study of variations in anterograde mitral flow revealed a sensitivity of 40% (27-53) and specificity of 87% (78-96). Variations in sub-aortic flow were analysed only in the final 27 patients, with a sensitivity and specificity of 100%. The specificity of dipyridamole echocardiography after infarction is good, both for the detection of residual stenosis and that of multiple vessel disease, the chief limiting factor being the impossibility of analysis of the infarcted region in the presence of initial akinesis.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Dipyridamole , Echocardiography, Doppler , Myocardial Infarction/diagnostic imaging , Adult , Constriction, Pathologic , Coronary Angiography , Coronary Disease/diagnostic imaging , Coronary Disease/prevention & control , Evaluation Studies as Topic , Female , Humans , Male , Middle Aged , Myocardial Infarction/drug therapy
3.
Arch Mal Coeur Vaiss ; 86(7): 1039-45, 1993 Jul.
Article in French | MEDLINE | ID: mdl-8291939

ABSTRACT

The objectives of this report were to analyse clinical presentation, echocardiographic features and diagnostic and therapeutic problems posed by an unusual form of thrombo-embolic disease: mobile right heart thrombosis. Systematic echocardiography in 170 cases of severe pulmonary embolism identified mobile right thrombi in 12 cases. The auscultatory findings were abnormal in 6 cases, 3 showing signs of tricuspid obstruction. Two-dimensional echocardiography showed an extremely mobile right atrial mass, sometimes prolapsing across the tricuspid valve, which was variously spheric, ovoid or worm-like; dilatation of the right heart chambers and echocardiographic signs of cor pulmonale were observed in all cases. The differential diagnosis with other embolic masses of the right atrium and, above all, with well-developed Chiari networks, may be difficult and requires transoesophageal echocardiography. Pulmonary angiography is contra-indicated because of the risk of embolism. Embolectomy under cardiopulmonary bypass was carried out in 8 patients, immediately after echocardiography in 6 cases. The thrombus was recovered from the right atrium in 6 cases and from the pulmonary artery in 2 cases: there was one operative death. Medical treatment was administered to 3 inoperable patients. The clinical and echocardiographic outcome was good in 2 of these but the third patient died; autopsy revealed thrombi in the right atrium and pulmonary artery. One patient died before any treatment could be given and autopsy showed the thrombus in the pulmonary artery. These results confirm the extreme instability of this type of thrombus and the risk of death due to its embolism.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Echocardiography , Heart Diseases/diagnostic imaging , Pulmonary Embolism/complications , Thrombosis/diagnostic imaging , Adult , Aged , Aged, 80 and over , Atrial Function, Right , Diagnosis, Differential , Embolectomy/methods , Emergencies , Female , Heart Atria , Heart Diseases/etiology , Heart Diseases/therapy , Humans , Male , Middle Aged , Pulmonary Embolism/therapy , Thrombosis/etiology , Thrombosis/therapy
4.
Ann Cardiol Angeiol (Paris) ; 42(4): 205-8, 1993 Apr.
Article in French | MEDLINE | ID: mdl-8517598

ABSTRACT

A case of pericarditis in a 52-year old patient following aorto-coronary shunt surgery is reported which gradually developed into chronic constrictive pericarditis. In this context, the diagnostic criteria of chronic constrictive pericarditis are recalled. The clinical criteria show little specificity; Doppler ultrasound provides good diagnostic information; CT scans and nuclear magnetic imaging can confirm the diagnostic. The post-heart surgery etiology has increased in recent years. The only real treatment is surgical and consists of pericardial decortication.


Subject(s)
Coronary Artery Bypass/adverse effects , Pericarditis, Constrictive/etiology , Chronic Disease , Humans , Male , Middle Aged , Pericardial Effusion/complications , Pericarditis, Constrictive/diagnosis
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