1.
Org Lett
; 16(6): 1794-7, 2014 Mar 21.
Article
in English
| MEDLINE
| ID: mdl-24611474
ABSTRACT
Photolabile linkers are an attractive alternative for solid-phase synthesis because they can be cleaved using light. However, irradiation in a classical batch photoreactor results in incomplete cleavage of the photolabile linkers. It is demonstrated that a continuous flow photoreactor is superior to a batch photoreactor for the cleavage of a linker from polystyrene resin.