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2.
Arkh Patol ; 51(10): 18-25, 1989.
Article in Russian | MEDLINE | ID: mdl-2610600

ABSTRACT

Biopsy material from two groups of patients with liver diseases is studied. 12 patients with a high titer of total anti-delta (D)-antibodies are included into the 1st group. In this group, among patients with total antibodies to D-infection D-antigen in the liver tissue is found in 6 cases with a pronounced chronic aggressive hepatitis (CAH) and active liver cirrhosis (ALC). The 2nd group consisted of 30 patients with CAH and ALC and D-antigen was observed in 10 cases. Hepatocyte degeneration and pronounced lobular infiltration were the only distinctive feature of liver morphology in D-positive cases as compared to the D-negative ones. The presence of D-antigen always correlated with an active inflammatory process.


Subject(s)
Hepatitis D/pathology , Liver/pathology , Adolescent , Adult , Aged , Antigens, Viral/analysis , Biopsy , Chronic Disease , Female , Hepatitis Antibodies/analysis , Hepatitis D/enzymology , Hepatitis D/immunology , Hepatitis Delta Virus/immunology , Histocytochemistry , Humans , Liver/enzymology , Liver/immunology , Male , Middle Aged , Retrospective Studies
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