ABSTRACT
Several studies have demonstrated that medical students and doctors rank specialties differently in terms of perceived status and prestige. At the same time some of the specialties have problems with recruiting and retaining staff. This study aimed to understand what constitutes status and prestige in the medical field and how it influences medical doctors' choice of specialty. By using a sociological perspective and applying Bourdieu's theoretical concepts of field, symbolic capital and perceived status, we analysed young doctors' journeys towards their chosen specialty. We conducted 15 in-depth semi-structured interviews. The data was analysed using content analysis. The findings suggest that medical specialties carry different social status. In the field of power, surgery is seen as the most prestigious of all specialties. However, in the future it might be a less attractive choice when young doctors tend to view their profession less as an identity and more like a job. For specialties perceived as low status, the challenge is to raise popularity by better describing to young doctors the characteristics and advantages of these specialties.
Subject(s)
Career Choice , Medicine , Models, Theoretical , Physicians/psychology , Social Class , Adult , Female , Humans , Interviews as Topic , Male , Qualitative Research , Self ConceptABSTRACT
BACKGROUND: The COMT (Catechol-O-Methyl Transferase) gene may influence a person's vulnerability to develop long-term pain and some COMT single nucleotide polymorphisms (SNPs) may associate with patterns of acute or chronic pain. Many patients with whiplash-associated disorders (WADs) suffer from long-term pain and other related symptoms, but it is less known if genetic factors play a role in the recovery process. The primary aim of this study was to evaluate whether self-reported non-recovery, including pain, was related to COMT genotype in patients with WAD. The secondary aim was to investigate whether or not background factors, including mental health, were related to genotype and non-recovery. METHODS: A total of 133 patients with neck pain after a whiplash trauma were included. Background factors were collected and blood samples were taken during the acute phase after the accident. DNA was isolated from blood and used to genotype the SNPs rs6269, rs4633, rs4818 and rs4680 in the COMT gene; additionally haplotypes were estimated and haplogenotypes inferred. The patients were followed up after 12 months and asked to rate their recovery including pain, mental health and quality of life. RESULTS: The overall reported non-recovery rate at 12 months was 44% with no significant differences in distribution of the COMT haplotypes. High levels of self-reported pain (OR 7.2) and anxiety (OR 4.4) after the accident were associated with non-recovery, but not related to the haplotypes. None of the other background factors were related to the haplotypes or non-recovery. CONCLUSION: No association between self-reported non-recovery or pain levels and COMT haplotypes in patients with acute whiplash injuries could be detected. Independent replications are necessary to discard the hypothesis that COMT haplotypes do not influence non-recovery or pain levels in patients with acute whiplash injuries. High levels of initial pain and anxiety were associated with non-recovery, thereby confirming previously published reports.
Subject(s)
Anxiety/psychology , Catechol O-Methyltransferase/genetics , Chronic Pain/genetics , Neck Pain/genetics , Whiplash Injuries/complications , Adult , Chronic Pain/etiology , Chronic Pain/psychology , Chronic Pain/therapy , Europe , Female , Follow-Up Studies , Haplotypes/genetics , Humans , Male , Middle Aged , Neck Pain/etiology , Neck Pain/psychology , Neck Pain/therapy , Pain Measurement , Polymorphism, Single Nucleotide , Quality of Life , Randomized Controlled Trials as Topic , Self Report , Whiplash Injuries/psychology , Whiplash Injuries/therapyABSTRACT
PURPOSE: The role of inflammation and fibrinolysis for the development of back pain and sciatica has been discussed. The aim of this study was to assess the relationship between markers of inflammation and fibrinolysis, to predict the outcome after surgery for lumbar disc herniation. METHODS: 177 patients were recruited. High sensitive C-reactive protein (hsCRP), plasminogen activator inhibitor 1 (PAI-1), fibrinogen, and D-dimer were analyzed preoperatively. Visual analogue scale (VAS) for back and leg pain, Oswestry Disability Index (ODI), and EuroQol 5 Dimensions (EQ-5D) were assessed preoperatively and at 6 weeks, 6-, 12-, and 24- months postoperatively. Dichotomization was made at the median for the laboratory analyses, and between the worst quartile and the other three quartiles for the outcome variables. Logistic regression was used to determine the odds ratios (OR) and 95 % confidence intervals (CI). RESULTS: The associations between PAI-1 and outcome seemed to be most prominent at the 6 and 12-month follow-up. When being in the upper half of PAI-1, the OR for being in the worst quartile of VAS back pain 12 months postoperatively was 3.33 (1.56-7.10). The corresponding OR for VAS leg pain was 2.46 (1.18-5.10), for ODI 2.83 (1.35-5.94) and for EQ-5D 2.73 (1.30-5.75). The OR for hsCRP was 2.10 (1.03-4.29) for being in the worst quartile of VAS back pain. Fibrinogen or D-dimer was not associated with any outcome variable. CONCLUSIONS: High PAI-1, a marker of fibrinolysis, was fairly consistently associated with poor outcome, while hsCRP, fibrinogen, and D-dimer were not.
Subject(s)
Fibrinolysis , Inflammation/diagnosis , Intervertebral Disc Displacement/surgery , Lumbar Vertebrae/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Back Pain/diagnosis , Back Pain/etiology , Biomarkers/blood , Female , Follow-Up Studies , Humans , Inflammation/blood , Inflammation/etiology , Intervertebral Disc Displacement/blood , Intervertebral Disc Displacement/complications , Intervertebral Disc Displacement/physiopathology , Logistic Models , Male , Middle Aged , Odds Ratio , Pain Measurement , Prospective Studies , Sciatica/diagnosis , Sciatica/etiology , Treatment Outcome , Young AdultABSTRACT
The aim of this randomised controlled study was to compare functional and radiological outcomes between modern cemented and uncemented hydroxyapatite coated stems after one year in patients treated surgically for a fracture of the femoral neck. A total of 141 patients aged > 65 years were included. Patients were randomised to be treated with a cemented Exeter stem or an uncemented Bimetric stem. The patients were reviewed at four and 12 months. The cemented group performed better than the uncemented group for the Harris hip score (78 vs 70.7, p = 0.004) at four months and for the Short Musculoskeletal Function Assesment Questionnaire dysfunction score at four (29.8 vs 39.2, p = 0.007) and 12 months (22.3 vs 34.9, p = 0.001). The mean EQ-5D index score was better in the cemented group at four (0.68 vs 0.53, p = 0.001) and 12 months (0.75 vs 0.58, p = < 0.001) follow-up. There were nine intra-operative fractures in the uncemented group and none in the cemented group. In conclusion, our data do not support the use of an uncemented hydroxyapatite coated stem for the treatment of displaced fractures of the femoral neck in the elderly.
Subject(s)
Arthroplasty, Replacement, Hip/methods , Cementation/methods , Femoral Neck Fractures/surgery , Hip Prosthesis , Activities of Daily Living , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/adverse effects , Arthroplasty, Replacement, Hip/instrumentation , Arthroplasty, Replacement, Hip/rehabilitation , Durapatite , Female , Femoral Neck Fractures/diagnostic imaging , Femoral Neck Fractures/rehabilitation , Hip Joint/diagnostic imaging , Hip Joint/physiopathology , Humans , Male , Periprosthetic Fractures/diagnostic imaging , Periprosthetic Fractures/etiology , Prosthesis Design , Radiography , Recovery of Function , Treatment OutcomeSubject(s)
Attitude of Health Personnel , Cardiopulmonary Resuscitation/psychology , Fear/psychology , Health Personnel/psychology , Cardiopulmonary Resuscitation/methods , Cross-Sectional Studies , Female , Finland , Health Care Surveys , Heart Arrest/therapy , Humans , Male , Needs Assessment , SwedenABSTRACT
The aim of this study was to investigate the epidemiology of fractures of the distal radius in the Swedish population and to review the methods used to treat them between 2005 and 2010. The study population consisted of every patient in Sweden who was diagnosed with a fracture of the wrist between 1 January 2005 and 31 December 2010. There were 177 893 fractures of the distal radius. The incidence rate in the total population was 32 per 10 000 person-years. The mean age of the patients was 44 years (0 to 104). The proportion of fractures treated operatively increased from 16% in 2005 to 20% in 2010. The incidence rate for plate fixation in the adult population increased 3.61 fold. The incidence rate for external fixation decreased by 67%. The change was greatest in the 50 years to 74 years age group. In Sweden, there is an increasing tendency to operate on fractures of the distal radius. The previously reported increase in the use of plating is confirmed: it has increased more than threefold over a five-year period.
Subject(s)
Fracture Fixation/trends , Radius Fractures/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Bone Plates , Child , Child, Preschool , Female , Fracture Fixation/statistics & numerical data , Fracture Fixation, Internal/statistics & numerical data , Fracture Fixation, Internal/trends , Fractures, Closed/epidemiology , Fractures, Closed/surgery , Fractures, Open/epidemiology , Fractures, Open/surgery , Humans , Incidence , Infant , Male , Middle Aged , Radius Fractures/epidemiology , Sweden/epidemiology , Treatment Outcome , Young AdultABSTRACT
OBJECTIVE: The objective structured examination is one of the most valid, reliable, and effective tools for assessing clinical and communication skills, often by use of standard patients (SPs). SPs can also be assessors of those skills. One of the crucial areas when utilizing SP-based assessment is the quality and consistency assurance of their portrayal of the case and their ability to fill in checklists in an adequate way. The aim of this study was to assess the validity and reliability of SPs' ability to assess students' communication skill via a Calgary-Cambridge checklist. METHOD: This cross-sectional and correlational study was conducted at the Tehran University of Medical Science. We first analyzed validity; the criterion validity of the SPs' filling in the checklists was assessed through determining the correlation between the SPs' completed checklists and the checklists filled in by three physician raters individually and then reproducibility: it was assessed by a test-retest approach inter-rater reliability. RESULT: The mean correlation for assessing the validity of SPs' completed checklists by individual SPs was 0.81. The inter-rater reliability was calculated by kappa coefficient, and the total correlation among the three raters was 0.85. The reliability of the test-retest approach showed no significant differences between the test and re-test results. CONCLUSION: The increased number of medical students and different faculties' responsibilities such as doing educational, research, and health services duties assessing medical student communication skills is a complex issue. The results of our study showed that trained SPs can be used as a valid tool to assess medical students' communication skills, which is also more cost effective and reduces work load of medical faculties.
Subject(s)
Clinical Competence/standards , Communication , Patient Simulation , Physician-Patient Relations , Students, Medical , Adult , Checklist , Cross-Sectional Studies , Educational Measurement/methods , Educational Measurement/standards , Female , Humans , Male , Middle Aged , Quality Assurance, Health Care , Reproducibility of Results , Young AdultABSTRACT
INTRODUCTION: Diabetes mellitus confers an increased risk of hip fractures. There is a limited knowledge of how the outcome after a hip fracture in patients with diabetes affect Health Related Quality of Life (HRQoL). The primary aim of this study was to evaluate HRQoL. Secondary aims were reoperation rate, complications and functions in patients with diabetes followed for 2 years after a hip fracture. MATERIALS AND METHODS: Out of 2133 patients diabetes was present in 234 patients (11%). Main outcome measurements were HRQoL evaluated with EuroQoL 5-Dindex score, reoperation rate, surgical and medical complications, function as walking ability, daily activities, living condition and pain. RESULTS: Preoperatively, patients with diabetes mellitus had more pain (p=0.044), co-morbidities, reduced health status (p=0.001) and more often used a walking frame (p=0.014) than patients without diabetes, whereas Katz ADL index, cognition and body mass index did not differ. There was no difference in fracture type, surgical method or reoperation between the two groups or between patients with insulin treated or oral treated diabetes. The EQ-5Dindex score decreased from 0.64 at admission to 0.45 at 4 months, 0.49 at 12 months and 0.51 at 24 months with similar results for patients with and without diabetes. During the first postoperative year there was not more medical complications among patients with diabetes, however cardiac (p=0.023) and renal failure (p=0.032) were more frequent in patients with diabetes at 24 months. Patients with diabetes more often had severe hip pain at 4 months (p=0.031). At 12 months more diabetic patients were living independently (p=0.034). There was no difference in walking ability, ADL and living condition between the groups at 24 months. CONCLUSION: The findings of this study indicate that patients with diabetes mellitus had more pain, co-morbidities, reduced health status preoperatively than patients without diabetes. Hip fracture patients with diabetes mellitus have more hip pain at 4 months. Cardiac and renal failure was more frequent in patients with diabetes at 24 months but otherwise we found a comparable re-operation rate, function and deterioration of Health Related Quality of Life as patients without diabetes within 2 years after a hip fracture.
Subject(s)
Diabetes Mellitus/physiopathology , Fracture Fixation, Intramedullary/methods , Hip Fractures/physiopathology , Pain, Postoperative/physiopathology , Activities of Daily Living/psychology , Aged, 80 and over , Diabetes Mellitus/mortality , Diabetes Mellitus/psychology , Female , Follow-Up Studies , Fracture Fixation, Intramedullary/mortality , Hip Fractures/mortality , Hip Fractures/psychology , Hip Fractures/surgery , Humans , Male , Pain, Postoperative/mortality , Pain, Postoperative/psychology , Prospective Studies , Quality of Life/psychology , Reoperation/statistics & numerical data , Survival Rate , Sweden/epidemiology , Treatment Outcome , WalkingABSTRACT
BACKGROUND: This study focuses on a skills test based clinical assessment where 118 fourth-year medical students at the four teaching hospitals of Karolinska Institutet participated in the same 12-module OSCE. The goal of one of the twelve examination modules was to assess the students' skills and ability to solve a virtual patient (VP) case (the ISP system), which included medical history taking, lab tests, physical examinations and suggestion of a preliminary diagnosis. AIMS: The primary aim of this study was to evaluate the potential of a VP as a possible tool for assessment of clinical reasoning and problem solving ability among medical students. The feeling of realism of the VP and its possible affective impact on the student's confidence were also investigated. METHOD: We observed and analysed students' reactions, engagement and performance (activity log files) during their interactive sessions with the simulation. An individual human assistant was provided along with the computer simulation and the videotaped interaction student/assistant was then analysed in detail and related to the students' outcomes. RESULTS: The results indicate possible advantages of using ISP-like systems for assessment. The VP was for instance able to reliably differentiate between students' performances but some weaknesses were also identified, like a confounding influence on students' outcomes by the assistants used. Significant differences, affecting the results, were found between the students in their degree of affective response towards the system as well as the perceived usefulness of assistance. CONCLUSION: Students need to be trained beforehand in mastering the assessment tool. Rating compliance needs to be targeted before VP-based systems like ISP can be used in exams and if such systems would be used in high-stake exams, the use of human assistants should be limited and scoring rubrics validated (and preferably automated).
Subject(s)
Computer Simulation , Educational Measurement , Patient Simulation , Adult , Clinical Competence/standards , Female , Humans , Male , Observation , Pilot Projects , Students, Medical , Surveys and Questionnaires , Videotape RecordingABSTRACT
The objective of this study was to further explore the safety of Hemospan (Sangart Inc., San Diego, CA, USA), an oxygen-carrying plasma expander. The aim of this study was to determine if Hemospan is well tolerated in orthopaedic surgery patients with spinal anaesthesia in doses up to 1 L. Hemospan was previously found to be well tolerated in normal volunteers and orthopaedic surgery patients with spinal anaesthesia in doses up to 500 mL. Five cohorts of six orthopaedic surgery patients, American Society of Anesthesiologists (ASA) I and II, were studied. In each cohort, four patients received Hemospan in doses ranging from 200 to 1000 mL, and two received Ringer's lactate immediately prior to induction of spinal anaesthesia. There were no serious adverse events (SAEs). Iohexol clearance measured before and 24 h after dosing was unaffected. There were 14 adverse events (AEs) in the 10 control patients (1.4 per patient) and 30 in the 20 patients receiving Hemospan (1.5 per patient). One patient in the group receiving 200 mL Hemospan had elevated mean arterial pressure after dosing, but there were no elevations in any of the other patients. The peak plasma Hemospan concentration in the 1000 mL group was 1.3 g dL(-1), with a dose-dependent clearance (T(1/2)) ranging from 14.1 to 23.0 h. Plasma methaemoglobin levels were independent of dose, reaching a maximum at 40 h after dosing and never exceeded 0.125 g dL(-1). Troponin T was transiently elevated in two patients receiving Hemospan without symptoms or electrocardiographic abnormalities or elevation of myocardial creatinine kinase isoenzyme. Hemospan was well tolerated in this group of patients at doses up to 1000 mL.
Subject(s)
Anesthesia, Spinal , Orthopedic Procedures , Plasma Substitutes/administration & dosage , Adult , Aged , Blood Pressure/drug effects , Cohort Studies , Contrast Media/administration & dosage , Contrast Media/pharmacokinetics , Dose-Response Relationship, Drug , Female , Humans , Iohexol/administration & dosage , Iohexol/pharmacokinetics , Isotonic Solutions/administration & dosage , Isotonic Solutions/adverse effects , Isotonic Solutions/pharmacokinetics , Male , Middle Aged , Plasma Substitutes/adverse effects , Plasma Substitutes/pharmacokinetics , Ringer's Lactate , Single-Blind Method , Time FactorsABSTRACT
The best treatment for the active and lucid elderly patient with a displaced intracapsular fracture of the femoral neck is still controversial. Randomised controlled trials have shown that a primary total hip replacement is superior to internal fixation as regards the need for secondary surgery, hip function and health-related quality of life. Despite good results achieved with total hip replacement in this group, most orthopaedic surgeons still advocate hemiarthroplasty for this injury. We studied 120 patients with a mean age of 81 years (70 to 90) with an acute displaced intracapsular fracture of the femoral neck. They were randomly allocated to be treated with either a bipolar hemiarthroplasty or total hip replacement. Outcome measurements included peri-operative data, general and hip-specific complications, hip function and health-related quality of life. The patients were reviewed at four and 12 months. The duration of surgery was longer in the total hip replacement group (102 minutes (70 to 151)) versus 78 minutes (43 to 131) (p<0.001), and the intra-operative blood loss was increased 460 ml (100 to 1100) versus 320 ml (50 to 850) (p<0.001), but there were no differences between the groups regarding any complications or mortality. There were no dislocations in either group. Hip function measured by the Harris hip score was significantly better in the total hip replacement group at both follow-up periods (p=0.011 and p<0.001, respectively). The health-related quality of life measure was in favour of the total hip replacement group but did not reach statistical significance (p=0.818 at four months and p=0.636 at 12 months). These results indicate that a total hip replacement provides better function than a bipolar hemiarthroplasty as soon as one year post-operatively, without increasing the complication rate. We recommend total hip replacement as the primary treatment for this group of patients.
Subject(s)
Arthroplasty, Replacement, Hip/methods , Femoral Neck Fractures/surgery , Activities of Daily Living , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/adverse effects , Arthroplasty, Replacement, Hip/rehabilitation , Female , Femoral Neck Fractures/rehabilitation , Follow-Up Studies , Hip Joint/physiopathology , Humans , Male , Quality of Life , Recovery of Function , Treatment OutcomeABSTRACT
We studied the epidemiology of 401 fractures of the shaft of the humerus in 397 patients aged 16 years or older. The incidence was 14.5 per 100,000 per year with a gradually increasing age-specific incidence from the fifth decade, reaching almost 60 per 100, 000 per year in the ninth decade. Most were closed fractures in elderly patients which had been sustained as the result of a simple fall. The age distribution in women was characterised by a peak in the eighth decade while that in men was more even. Simple fractures were by far the most common and most were located in the middle or proximal shaft. The incidence of palsy of the radial nerve was 8% and fractures in the middle and distal shaft were most likely to be responsible. Only 2% of the fractures were open and 8% were pathological. These figures are representative of a population with a low incidence of high-energy and penetrating trauma, which probably reflects the situation in most European countries.
Subject(s)
Humeral Fractures/epidemiology , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Female , Fractures, Closed/epidemiology , Humans , Humeral Fractures/complications , Incidence , Male , Middle Aged , Neoplasms/complications , Neoplasms/epidemiology , Radial Neuropathy/epidemiology , Radial Neuropathy/etiology , Sex Distribution , Sweden/epidemiologyABSTRACT
BACKGROUND: Phlebography is regarded as the reference standard for diagnosing asymptomatic deep vein thrombosis (DVT) in studies of thromboprophylaxis. However, technical advances with noninvasive color duplex sonography (CDS) have made this procedure an interesting alternative. OBJECTIVES: The objective of the present prospective study was to compare the sensitivity and specificity of CDS with those of phlebography. PATIENTS: The first 180 consecutive patients included in a larger randomized trial for prolonged thromboprophylaxis were subject to unilateral CDS and to phlebography after ankle fracture surgery. The patients were examined 6 weeks after surgery, all examinations being evaluated blindly. After patient drop outs and exclusions, 144 patients were left for analysis. RESULTS: Phlebography and CDS examinations were inconclusive or were not completed for 19% of these patients (28/144). DVT was diagnosed by phlebography in 21% (24/116) of the remaining patients. Most of the thrombi were isolated calf DVTs (18/24). In contrast, DVT was diagnosed by CDS in 31% of these patients (36/116): only one case diagnosed by phlebography was missed by CDS. The specificity of CDS is thus 86% and its sensitivity is 96%. The positive predictive value is 64%, and the negative predictive value is 99%. CONCLUSIONS: CDS is a safe method for detecting asymptomatic distal DVT. It has a high sensitivity and high negative predictive value, which means that the method is highly reliable to rule out DVT. Our results indicate that CDS could be considered as an alternative method for DVT screening.
Subject(s)
Ankle Injuries/surgery , Fractures, Bone/surgery , Ultrasonography, Doppler, Color/methods , Venous Thrombosis/diagnosis , Venous Thrombosis/pathology , Adolescent , Adult , Aged , Ankle/pathology , Double-Blind Method , Female , Humans , Male , Middle Aged , Phlebography/methods , Placebos , Prospective Studies , Sensitivity and SpecificityABSTRACT
OBJECTIVE: To study appetite and food choices in lean elderly women at the time of a femoral neck fracture and after 6 months of nutritional and anabolic intervention. SUBJECTS AND METHODS: Forty-five nondemented women >70 years of age (mean +/- SD: 83 +/- 5 years) with a recent hip fracture and body mass index <24 kg/m2 (mean: 20.5 +/- 2.3) were interviewed about their appetite and dietary habits prior to fracture. The patients were randomized to treatment with a protein-rich liquid supplement (PR; 200 kcal and 20 g protein day(-1)) alone or in combination with nandrolone decanoate injections (PR/N) 25 mg i.m. every third week or to a control group (C). A second interview was conducted 6 months later. RESULTS: Reduced appetite before the fracture was reported by 60%. Half of the patients did not have dessert with any of their daily meals, one-third used low-fat margarines and one-third drank water with their meals. The estimated mean daily energy intake was 6.4 +/- 1.2 MJ (1541 +/- 304 kcal) indicating that three of four subjects did not meet their energy needs. At 6 months, 40% reported reduced appetite. There was no difference in the change of appetite between the three randomized groups. Still, half of the subjects appeared to not meet their energy needs. Protein intake increased in the PR and PR/N groups, in contrast to the controls (P = 0.002). CONCLUSION: Reduced appetite and insufficient energy intake was recorded in lean elderly women with a femoral neck fracture. Nutritional supplementation alone or in combination with an anabolic steroid increased protein intake without adversely affecting appetite.
Subject(s)
Aging , Anabolic Agents/administration & dosage , Appetite , Feeding Behavior , Femoral Neck Fractures/therapy , Nandrolone/analogs & derivatives , Nutritional Support , Aged , Aged, 80 and over , Body Mass Index , Dietary Proteins/administration & dosage , Dietary Supplements , Energy Intake , Female , Food Preferences , Fractures, Bone , Humans , Nandrolone/administration & dosage , Nandrolone DecanoateABSTRACT
We studied 60 patients with an acute displaced fracture of the femoral neck and with a mean age of 84 years. They were randomly allocated to treatment by either internal fixation with cannulated screws or hemiarthroplasty using an uncemented Austin Moore prosthesis. All patients had severe cognitive impairment, but all were able to walk independently before the fracture. They were reviewed at four, 12 and 24 months after surgery. Outcome assessments included complications, revision surgery, the status of activities of daily living (ADL), hip function according to the Charnley score and the health-related quality of life (HRQOL) according to the Euroqol (EQ-5D) (proxy report). General complications and the rate of mortality at two years (42%) did not differ between the groups. The rate of hip complications was 30% in the internal fixation group and 23% in the hemiarthroplasty group; this was not significant. There was a trend towards an increased number of re-operated patients in the internal fixation group compared with the hemiarthroplasty group, 33% and 13%, respectively (p = 0.067), but the total number of surgical procedures which were required did not differ between the groups. Of the survivors at two years, 54% were totally dependent in ADL functions and 60% were bedridden or wheelchair-bound regardless of the surgical procedure. There was a trend towards decreased mobility in the hemiarthroplasty group (p = 0.066). All patients had a very low HRQOL even before the fracture. The EQ-5D(index) score was significantly worse in the hemiarthroplasty group compared with the internal fixation group at the final follow-up (p < 0.001). In our opinion, there is little to recommend hemiarthroplasty with an uncemented Austin Moore prosthesis compared with internal fixation, in patients with severe cognitive dysfunction.
Subject(s)
Arthroplasty, Replacement, Hip , Cognition Disorders/complications , Femoral Neck Fractures/surgery , Fracture Fixation, Internal , Activities of Daily Living , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/rehabilitation , Female , Femoral Neck Fractures/complications , Femoral Neck Fractures/rehabilitation , Follow-Up Studies , Fracture Fixation, Internal/rehabilitation , Hip Joint/physiopathology , Hip Prosthesis , Humans , Male , Quality of Life , Range of Motion, Articular , Survival Rate , Treatment OutcomeABSTRACT
We studied 217 patients with an unstable trochanteric or subtrochanteric fracture who had been randomly allocated to treatment by either internal fixation with a standard Gamma nail (SGN) or a Medoff sliding plate (MSP, biaxial dynamisation mode). Their mean age was 84 years (65 to 99) and they were reviewed at four and 12 months after surgery. Assessments of outcome included general complications, technical failures, revision surgery, activities of daily living (ADL), hip function (Charnley score) and the health-related quality of life (HRQOL, EQ-5D). The rate of technical failure in patients with unstable trochanteric fractures was 6.5% (6/93) (including intra-operative femoral fractures) in the SGN group and 5.2% (5/96) in the MSP group. In patients with subtrochanteric fractures, there were no failures in the SGN group (n = 16) and two in the MSP group (n = 12). In the SGN group, there were intra-operative femoral fractures in 2.8% (3/109) and no post-operative fractures. There was a reduced need for revision surgery in the SGN group compared with the MSP group (8.3%; 9/108; p = 0.072). The SGN group also showed a lower incidence of severe general complications (p < 0.05) and a trend towards a lower incidence of wound infections (p = 0.05). There were no differences between the groups regarding the outcome of ADL, hip function or the HRQOL. The reduction in the HRQOL (EQ-5D(index) score) was significant in both groups compared with that before the fracture (p < 0.005). Our findings indicate that the SGN showed good results in both trochanteric and subtrochanteric fractures. The limited number of intra-operative femoral fractures did not influence the outcome or the need for revision surgery. Moreover, the SGN group had a reduced number of serious general complications and wound infections compared with the MSP group. The MSP in the biaxial dynamisation mode had a low rate of failure in trochanteric fractures but an unacceptably high rate when used in the biaxial dynamisation mode in subtrochanteric fractures. The negative influence of an unstable trochanteric or subtrochanteric fracture on the quality of life was significant regardless of the surgical method.
Subject(s)
Bone Nails , Bone Plates , Fracture Fixation, Internal/methods , Hip Fractures/surgery , Activities of Daily Living , Aged , Aged, 80 and over , Female , Follow-Up Studies , Fracture Fixation, Internal/rehabilitation , Fracture Fixation, Intramedullary/methods , Fracture Fixation, Intramedullary/rehabilitation , Hip Fractures/rehabilitation , Hip Joint/physiopathology , Humans , Male , Postoperative Complications , Quality of Life , Reoperation , Treatment OutcomeABSTRACT
OBJECTIVES: To evaluate the responsiveness of the EuroQol (EQ-5D) and Short-Form 36 (SF-36) instruments, i.e. their ability to capture clinically important changes, in elderly patients with a displaced femoral neck fracture. The study was part of a prospective randomised study comparing two different surgical procedures, internal fixation (IF) and total hip replacement (THP). SETTING: University hospital. PATIENTS: A total of 110 patients, mean age 80 years with an acute displaced femoral neck fracture (Garden III and IV). The inclusion criteria were age > or = 70, absence of severe cognitive dysfunction, independent living status and independent walking capability. INTERVENTION: The patients were randomised to IF or to a THR. MAIN OUTCOME MEASUREMENTS: Health-related quality of life according to EQ-5D and SF-36. Responsiveness measured by the ability of the EQ-5D and the SF-36 to detect clinically relevant differences in the study population according to an external criterion (EC) for outcome (good or less good clinical outcome). Responsiveness was measured in terms of change scores, standardised effect size (SES) and standardised response mean (SRM). RESULTS: The rated prefracture EQ-5D(index) scores and SF-36 scores showed good correspondence with the scores of age-matched Swedish reference populations. The relationship between the EC and EQ-5D(index) score and the SF-36 global score showed significant differences in both comparisons (p < 0.001). The responsiveness expressed with the SES and SRM were large for both the EQ-5D (1.37 and 0.90, respectively) and for the SF-36 global score (0.89 and 0.82, respectively). The correlation between the change scores for the SF-36 global score and the EQ-5D was 0.39 (p < 0.001). CONCLUSION: The results showed high responsiveness for both the EQ-5D and the SF-36, indicating that both instruments are suitable for use as outcome measures in clinical trials in elderly hip fracture patients.
Subject(s)
Femoral Neck Fractures/physiopathology , Health Status Indicators , Interviews as Topic , Quality of Life , Accidental Falls , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip , Femoral Neck Fractures/surgery , Humans , Internal Fixators , Male , Prospective Studies , SwedenABSTRACT
The treatment algorithms for displaced fractures of the femoral neck need to be improved if we are to reduce the need for secondary surgery. We have studied 102 patients of mean age 80 years, with an acute displaced fracture of the femoral neck. They were randomly placed into two groups, treated either by internal fixation (IF) with two cannulated screws or total hip replacement (THR). None showed severe cognitive dysfunction, all were able to walk independently, and all lived in their own home. They were reviewed at four, 12 and 24 months after surgery. Outcome measurements included hip complications, revision surgery, hip function according to Charnley and the health-related quality of life (HRQoL) according to EuroQol (EQ-5D). The failure rate after 24 months was higher in the IF group than in the THR group with regard to hip complications (36% and 4%, respectively; p < 0.001), and the number of revision procedures (42% and 4%, p < 0.001). Hip function was significantly better in the THR group at all follow-up reviews regarding pain (p < 0.005), movement (p < 0.05 except at 4 months) and walking (p < 0.05). The reduction in HRQoL (EQ-5D index score) was also significantly lower in the THR group than in the IF group, comparing the pre-fracture situation with that at all follow-up reviews (p < 0.05). The results of our study strongly suggest that THR provides a better outcome than IF for elderly, relatively healthy, lucid patients with a displaced fracture of the femoral neck.
Subject(s)
Arthroplasty, Replacement, Hip/methods , Femoral Neck Fractures/surgery , Fracture Fixation, Internal/methods , Hip Prosthesis , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/rehabilitation , Female , Femoral Neck Fractures/complications , Femoral Neck Fractures/rehabilitation , Follow-Up Studies , Fracture Fixation, Internal/rehabilitation , Fracture Healing , Humans , Male , Quality of Life , Software Design , Survival Analysis , Treatment Failure , Treatment OutcomeABSTRACT
We compared the long-term outcome in 61 patients (62 fractures) treated operatively or conservatively for an acute fracture of the carpal scaphoid. A total of 30 fractures was randomised to conservative treatment using a cast and 32 to operative treatment using a Herbert bone screw. The duration of sick leave was shorter for patients treated by operation, but this was only significant in patients with blue-collar occupations. There were no differences between the groups in respect of function, radiological healing of the fracture, or carpal arthritis after follow-up at 12 years. Those managed by operation showed radiological signs of arthritis of the scaphotrapezial joint more often, but this finding did not correlate with subjective symptoms. Operative treatment of an acute fracture of the scaphoid allows early return of function and should be regarded as an alternative to conservative treatment in patients in whom immobilisation in a cast for three months is not acceptable for reasons related to sports, social life or work.
Subject(s)
Fractures, Bone/therapy , Scaphoid Bone/injuries , Adolescent , Adult , Arthritis/etiology , Bone Screws , Female , Follow-Up Studies , Fractures, Bone/complications , Fractures, Bone/diagnostic imaging , Humans , Male , Middle Aged , Prospective Studies , Radiography , Scaphoid Bone/diagnostic imagingABSTRACT
OBJECTIVES: To describe the outcome in a consecutive series of patients with tibial shaft fractures and to determine whether prospective registration of fracture care produces useful data for clinical purposes. DESIGN: A prospective follow-up study. SETTING: A large teaching hospital in Stockholm, Sweden. PATIENTS: Sixty-four consecutive patients with a tibial shaft fracture. INTERVENTION: Patients were surgically treated according to the protocols at our institute and were followed up prospectively for one year. MAIN OUTCOME MEASUREMENTS: Clinical outcome, functional results, Short Form 36 Health Survey, Olerud Molander Ankle score, visual analogue scale. RESULTS: The fractures were classified as 42A (61 percent), 42B (31 percent), and 42C (8 percent). Forty-three (67 percent) patients were treated with an interlocked tibial nail. The complication rate was low and associated with high-energy trauma. The quality of life according to the Short Form 36 Health Survey was diminished at four and twelve months after the injury, as compared with the preinjury status. Twelve months after the injury, 44 percent had not regained full function of the injured leg, although all but two of the patients had returned to preinjury working status. CONCLUSIONS: Although the complication rate was low, twelve months after the injury, nearly half the patients still experienced functional limitations related to the fracture, which was also reflected in the quality-of-life parameters. There were difficulties in retrieving data for this registry. We think that periodic, rather than continuous, registration of patient-related outcome after fracture treatment is more beneficial from a clinical and economic point of view.