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1.
Int J Food Sci Nutr ; 65(7): 821-6, 2014 Nov.
Article in English | MEDLINE | ID: mdl-24990165

ABSTRACT

The present investigation intends to evaluate the changes in the content of cis/trans carotene isomers as provitamin A carotenoids by steaming and roasting processes in the roots of four Korean sweet potato varieties viz. Shinzami, Younwhangmi, Chuwhangmi and Jinhongmi using a liquid chromatography with diode array detection and the negative ion atmospheric pressure chemical ionization mass spectrometric (LC-DAD-APCI/MS) method and UV spectral pattern library created from several reference data. Except Shinzami, the content of all trans ß-carotenes was found to slightly decreased or remained constant when steamed or roasted. The content of cis α-/ß-carotenes was potentially increased about 2-fold or greater when raw or steamed and the content was slightly decreased while roasted. In Chuwhangmi, the content of 13-cis α-carotene and all trans α-carotenes were rapidly increased when steamed and slightly decreased when roasted. Chuwhangmi exhibited 27.2 mg/100 g DW content of all trans ß-carotenes when roasted and thus, it was considered as a relatively superior cultivar.


Subject(s)
Carotenoids/chemistry , Food Handling/methods , Ipomoea batatas/chemistry , Ipomoea batatas/metabolism , Carotenoids/metabolism , Molecular Structure , Republic of Korea
2.
Eur J Med Chem ; 58: 464-9, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23151322

ABSTRACT

An elegant and efficient synthesis of hitherto novel 1,2,3-triazolyl dihydropyrimidine-2-thione hybrids has been accomplished for the first time in a green solvent viz. water. The hybrid molecules exhibit significant antibacterial activity when screened against four human pathogens viz. Streptococcus pneumonia, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella typhi. In comparison to the commercially marketed tetracycline, some of them were equally potent and a few more potent.


Subject(s)
Anti-Bacterial Agents/pharmacology , Pseudomonas aeruginosa/drug effects , Pyrimidines/pharmacology , Salmonella typhi/drug effects , Staphylococcus aureus/drug effects , Streptococcus pneumoniae/drug effects , Triazoles/pharmacology , Water/chemistry , Anti-Bacterial Agents/chemical synthesis , Anti-Bacterial Agents/chemistry , Dose-Response Relationship, Drug , Ethanol/chemistry , Microbial Sensitivity Tests , Molecular Structure , Pyrimidines/chemical synthesis , Pyrimidines/chemistry , Structure-Activity Relationship , Triazoles/chemical synthesis , Triazoles/chemistry
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