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1.
Rom J Morphol Embryol ; 58(2): 689-693, 2017.
Article in English | MEDLINE | ID: mdl-28730263

ABSTRACT

The role of arthroscopic surgery for the treatment of various orthopedic pathologies has greatly improved during the last years. Recent publications showed that benign bone lesion may benefit from this minimally invasive surgical method, in order to minimize the invasiveness and the period of immobilization and to increase visualization. Unicameral bone cysts may be adequately treated by minimally invasive endoscopic surgery. The purpose of the current paper is to present the case report of a patient with a unicameral bone cyst of the calcaneus that underwent endoscopically assisted treatment with curettage and bone grafting with allograft from a bone bank, with emphasis on the surgical technique. Unicameral bone cyst is a benign bone lesion, which can be adequately treated by endoscopic curettage and percutaneous injection of morselized bone allograft in symptomatic patients.


Subject(s)
Arthroscopy/methods , Bone Cysts/surgery , Calcaneus/surgery , Endoscopy/methods , Adult , Bone Cysts/pathology , Calcaneus/pathology , Humans , Male , Treatment Outcome , Young Adult
2.
Rom J Morphol Embryol ; 57(2 Suppl): 825-829, 2016.
Article in English | MEDLINE | ID: mdl-27833977

ABSTRACT

Endometriosis is a gynecologic condition affecting mainly the pelvic organs. However, extrapelvic endometriosis has been reported in almost all parts of the body. Umbilical endometriosis, either primary or secondary, is uncommon and has a documented neoplastic risk. We present the case of a 46-year-old woman with a large umbilical hernia associating primary umbilical endometriosis discovered during surgery and confirmed later by pathological and immunohistochemical exams. The patient underwent omphalectomy and partial omentum resection, alongside with mesh abdominal wall repair. The patient was informed about the recurrence risk and was asymptomatic at follow-up consults.


Subject(s)
Endometriosis/diagnosis , Hernia, Umbilical/diagnosis , Atrophy , Diagnosis, Differential , Endometriosis/pathology , Endometrium/pathology , Female , Hernia, Umbilical/pathology , Humans , Immunohistochemistry , Ki-67 Antigen/metabolism , Middle Aged
3.
Rom J Morphol Embryol ; 56(2): 537-43, 2015.
Article in English | MEDLINE | ID: mdl-26193225

ABSTRACT

Vulvar neoplasia represents 5% of malignancies in female genital tract and 0.6% of all cancers in women. Although it is known to be a rare type of cancer, which occurs especially in elderly women, its incidence is increasing in young females because of its association with the human papillomavirus (HPV). In this paper, we report the case of a 46-year-old woman, gravidity 4, parity 3, with a medical history of multiple vulvar excisions for recurrent ulcerative vulvar lesions during a period of 11 years. The first lesion appeared in 2003, it was excised and the histopathological result showed squamous cell carcinoma with undifferentiated areas and chronic ulcerative inflammation. The patient underwent radiation therapy remaining at the end of it a small-ulcerated lesion at the superior vulvar commissure, which was biopsied in 2004 showing chronic ulcerative inflammation with reparatory areas of squamous immature benign metaplasia In April 2014, a dermatological consult described vulvar scleroatrophic lichen confirmed by a biopsy. In November 2014, the patient presented to our clinic when a vicious vulvar scar was detected, with a transformed tegument with aspect of atrophic lichen. A perineal reconstruction including anal sphincter plasty was performed. Due to the important remaining skin defect, a Surgisis graft vulvoplasty was performed. The histopathological result of the excised suspect areas was vulvar intraepithelial high-grade neoplasia (VIN III). A retrospective histopathological review of the case established that is more accurate to consider that the vulvar lesions were, all along, a very well differentiated squamous cell carcinoma (verrucous carcinoma), which lacks cytopathic effect of HPV infection, has a low p53 expression but a high Ki67. Case evolution was favorable with the acceptance and integration of the biologic grafts at two months after surgery and normal healing.


Subject(s)
Carcinoma, Verrucous/surgery , Perineum/surgery , Plastic Surgery Procedures , Vulvar Neoplasms/surgery , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Carcinoma, Verrucous/pathology , Cell Differentiation , Female , Humans , Immunohistochemistry , Inflammation/pathology , Middle Aged , Neoplasm Proteins/metabolism , Vulvar Neoplasms/pathology
4.
Rev Med Chir Soc Med Nat Iasi ; 116(2): 595-9, 2012.
Article in English | MEDLINE | ID: mdl-23077959

ABSTRACT

Widening of the upper jaw by undoing the median suture is a relatively common clinical procedure and the histological studies on sutural tissues, both immediately after disjunction and post disjunction are relatively rare. The present research aims to study cellular changes caused after undoing the median maxillary suture, on a strain of common rabbit breed, in an attempt to prove that the purpose of this therapeutic technique is obtaining neoformed osseous tissue, as a guarantee of the stability of orthodontic treatment results. Of course, changes in rabbit desmale tissues cannot be fully assimilated to the human ones.


Subject(s)
Maxilla/surgery , Osteogenesis, Distraction/instrumentation , Suture Techniques , Animals , Disease Models, Animal , Orthodontic Appliances , Osteogenesis , Osteogenesis, Distraction/methods , Rabbits , Treatment Outcome
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