ABSTRACT
UNLABELLED: The authors present some observations regarding the use of topical anti-glaucoma therapy and systemic vasodilators. MATERIAL AND METHODS: The study was carried out on a series of 996 glaucoma patients, of which 54.1% with primary open-angle glaucoma, 5.7% closed-angle glaucoma, and 17.6% with normal intraocular pressure. RESULTS: Intraocular pressure and visual field were assessed after the use of such therapeutic methods as carbonic anhydrase inhibitors (dorzolamide) and prostaglandin (latanoprost) and dorzolamide (cosopt) association. CONCLUSIONS: The favorable progression of glaucoma could be improved by using new etiopathogenic mechanisms and treatment approaches.
Subject(s)
Antihypertensive Agents/administration & dosage , Glaucoma, Angle-Closure/drug therapy , Glaucoma, Open-Angle/drug therapy , Intraocular Pressure/drug effects , Prostaglandins F, Synthetic/administration & dosage , Sulfonamides/administration & dosage , Thiophenes/administration & dosage , Visual Fields/drug effects , Carbonic Anhydrase Inhibitors/administration & dosage , Drug Therapy, Combination , Follow-Up Studies , Glaucoma, Angle-Closure/physiopathology , Glaucoma, Open-Angle/physiopathology , Humans , Latanoprost , Ocular Hypertension/drug therapy , Ophthalmic Solutions/administration & dosage , Retrospective Studies , Treatment OutcomeABSTRACT
MATERIAL AND METHOD: The authors present the results of clinical and epidemiological research on a sample of 8118 patients assisted in the Ophthalmology Clinic of the Hospital "Prof. Dr. N. Oblu", including 996 (12.1%) with glaucoma, of which 54.1% primary open angle glaucoma (POAG), 22.6%, normal tension glaucoma (NTG), 5.7% primary angle closure-glaucoma (PACG) and 17.6% secondary glaucoma, during 2006-2010. RESULTS: For patients with glaucoma authors assessed the prevalence of arterial hypertension (POAG: 33.1%; NTG: 32%; PACG: 8.7%, secondary: 8%), diabetes mellitus (POAG : 19.9%, TNG : 12.9%; PACG : 5.3%, secondary : 5.2%), atherosclerosis (POAG: 10.2%, TNG: 12%; PACG: 5.2%, secondary: 2.9%), vasospasm (POAG: 45 2%, TNG: 47.3%; PACG: 39.3%, secondary: 44.3%).