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1.
Materials (Basel) ; 16(11)2023 May 30.
Article in English | MEDLINE | ID: mdl-37297209

ABSTRACT

Smart textiles recently reaped significant attention owing to their potential applications in various fields, such as environmental and biomedical monitoring. Integrating green nanomaterials into smart textiles can enhance their functionality and sustainability. This review will outline recent advancements in smart textiles incorporating green nanomaterials for environmental and biomedical applications. The article highlights green nanomaterials' synthesis, characterization, and applications in smart textile development. We discuss the challenges and limitations of using green nanomaterials in smart textiles and future perspectives for developing environmentally friendly and biocompatible smart textiles.

2.
Front Cell Infect Microbiol ; 12: 807253, 2022.
Article in English | MEDLINE | ID: mdl-35252028

ABSTRACT

Viral infections are a significant public health problem, primarily due to their high transmission rate, various pathological manifestations, ranging from mild to severe symptoms and subclinical onset. Laboratory diagnostic tests for infectious diseases, with a short enough turnaround time, are promising tools to improve patient care, antiviral therapeutic decisions, and infection prevention. Numerous microbiological molecular and serological diagnostic testing devices have been developed and authorised as benchtop systems, and only a few as rapid miniaturised, fully automated, portable digital platforms. Their successful implementation in virology relies on their performance and impact on patient management. This review describes the current progress and perspectives in developing micro- and nanotechnology-based solutions for rapidly detecting human viral respiratory infectious diseases. It provides a nonexhaustive overview of currently commercially available and under-study diagnostic testing methods and discusses the sampling and viral genetic trends as preanalytical components influencing the results. We describe the clinical performance of tests, focusing on alternatives such as microfluidics-, biosensors-, Internet-of-Things (IoT)-based devices for rapid and accurate viral loads and immunological responses detection. The conclusions highlight the potential impact of the newly developed devices on laboratory diagnostic and clinical outcomes.


Subject(s)
Biosensing Techniques , Communicable Diseases , Respiratory Tract Infections , Biosensing Techniques/methods , Humans , Microfluidics , Respiratory Tract Infections/diagnosis , Serologic Tests
3.
Biophys Chem ; 279: 106691, 2021 12.
Article in English | MEDLINE | ID: mdl-34600311

ABSTRACT

Surface plasmon resonance (SPR) is a label-free, real-time bio-sensing technique with high potential in the diagnostic area, especially when a signal amplification strategy is used to improve the detection limit. We report here a simple method for enhancing the detection limit of bovine serum albumin (BSA), by attaching gold nanorods (AuNRs). AuNRs were obtained by a seedless synthesis technique and characterized using scanning electron microscopy (SEM), UV-VIS spectroscopy, FT-IR spectroscopy and dynamic light scattering (DLS). Finite element method (FEM) simulations were employed to explore the enhancement of the SPR signal by adding AuNRs on the SPR sensor's metallic layer. SPR spectroscopy was used to analyze the changes in the refractive index brought by the immobilization of unconjugated BSA and BSA modified with AuNRs. The results confirmed that the AuNRs conjugated with the protein increase the SPR signal ~ 10 times, leading to a limit of detection of 1.081 × 10-8 M (0.713 µg/mL).


Subject(s)
Biosensing Techniques , Nanotubes , Biosensing Techniques/methods , Gold/chemistry , Nanotubes/chemistry , Serum Albumin, Bovine/chemistry , Spectroscopy, Fourier Transform Infrared , Surface Plasmon Resonance
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