Adaptive effects of dexamethasone in stress exposure.

Disorders in the compensatory adaptive processes underlie the development of many somatic diseases. The neuroimmunoendocrine complex and one of its main components, the hypothalamic-pituitary-adrenal system, play the leading role in the maintenance of the adaptation reserve. Treatment with a synthetic analog of hydrocortisone (final effector of this system) in low doses modulates its function by inducing positive changes in the adaptive mechanisms under conditions of stress exposure.

[Coagulase-negative staphylococci isolated from patients. I. Biological properties and biotyping of the strains]. / Koagulazootritsatel'nye stafilokokki, vydelennye ot bol'nykh. Soobshchenie I. biologicheskie svoistva i biotipirovanie shtammov.

A total of 403 coagulase- and DNAase-negative staphylococcal strains isolated from patients with conjunctivitis, urological diseases, purulent inflammatory processes, septicemia, infected traumas, pyodermia were investigated in 18 biological tests. In a vast majority of cases the absence of correlation between the individual biological characteristics of the strains was revealed. The identification of S. epidermidis and S. saprophyticus, carried out by Akatov et al. in accordance with the schemes of the International Subcommittee, Digranes and Oeding, allowed to determine the species the organisms under test belonged to in 26%, 38% and 64% of the strains, respectively. Most of the identified strains belonged to S. epidermidis. Their biological typing by the methods of Baird-Parker and Akatov-Khatenever allowed the biotype to be determined in 79% and 69% of the cultures. Strains belonging to biotype 1 according to Baird-Peter were most frequently isolated in conjunctivitis, purulent processes and pyodermia, while strains belonging to biotype 2 according to Akatov-Khatenever were prevalent in urological diseases.