1.
Antibiot Khimioter
; 33(1): 16-22, 1988 Jan.
Article
in Russian
| MEDLINE
| ID: mdl-3259864
ABSTRACT
The process of asymmetric deacylation of an acetyl derivative of 5-benzyl hydroxytryptophan racemate in the presence of native microbial aminoacylase was studied. The effect of pH, temperature, concentration of the enzyme and substrate were investigated. Conditions for preparation and isolation of individual amino acids were defined by optimization of N-Ac-DU-5-BOT hydrolysis.
Subject(s)
5-Hydroxytryptophan/analogs & derivatives , 5-Hydroxytryptophan/isolation & purification , Amidohydrolases/pharmacology , Tryptophan/analogs & derivatives , Acylation , Fermentation , Hydrogen-Ion Concentration , In Vitro Techniques , Kinetics , Regression Analysis , Solubility , Stereoisomerism , Temperature , Tryptophan/isolation & purification
2.
Khirurgiia (Mosk)
; (9): 24-6, 1985 Sep.
Article
in Russian
| MEDLINE
| ID: mdl-4057878