Subject(s)
Amino Acids/pharmacology , Antibody-Producing Cells/drug effects , Cytotoxicity, Immunologic/drug effects , Neutrophils/drug effects , Peptides/pharmacology , Phagocytosis/drug effects , Aflatoxins/pharmacokinetics , Aflatoxins/toxicity , Animals , Antibody-Producing Cells/immunology , Benzene/pharmacokinetics , Benzene/toxicity , Chickens , Dipeptides/pharmacology , In Vitro Techniques , Inactivation, Metabolic/immunology , Male , Mice , Neutrophils/immunology , Spleen/drug effects , Spleen/immunology , Thymus Hormones/chemistryABSTRACT
The influence of water-soluble polysaccharides of Viscum album L. on the survival of mice subjected to whole-body gamma-irradiation has been investigated. Polysaccharides were shown to exert a radioprotective effect which was a function of both the radiation dose and the drug dose and time of its injection. The maximum radioprotective efficacy of polysaccharides was observed after their injection 15 min before irradiation. A single intraperitoneal administration of polysaccharides (25 mg/kg) before irradiation with LD50/30 and LD100/10-12 increased the 60-day survival rate up to 95% and 27% respectively. The postirradiation injection of polysaccharides prevented death of 80% of mice given LD50 and increased the average life expectancy of animals irradiated with absolutely lethal doses.
Subject(s)
Cesium Radioisotopes/pharmacology , Plants , Polysaccharides/pharmacology , Radiation-Protective Agents , Animals , Lethal Dose 50 , Male , Mice , Polysaccharides/administration & dosage , Radiation Dosage , Time Factors , Whole-Body IrradiationABSTRACT
X-ray image of changes in facial skull bones and temporomandibular articulation in 75 children and adolescents with a history of traumatic or inflammatory diseases or surgery for benign mandibular tumors in childhood is described. The deformation type did not present the specific features indicating the cause of the defect; its severity depended on the length of the defect existence and the depth of the injury to the mandibular growth area. Deformations of the lower third of the facial skull commonly develop soon after the underlying disease; changes in the upper segments of the skull develop later. If skin plasty was carried out simultaneously with tumor removal no facial skull deformations developed or these deformations were but negligible. The longer was the existence of the defect, the more coarse and vast were the changes in facial skull bones, that needed a combined surgical and orthodontic management.
Subject(s)
Facial Bones/diagnostic imaging , Adolescent , Child , Child, Preschool , Facial Bones/injuries , Humans , Infant , Mandibular Diseases/diagnostic imaging , Mandibular Injuries/diagnostic imaging , Mandibular Neoplasms/diagnostic imaging , Osteomyelitis/diagnostic imaging , Radiography, PanoramicABSTRACT
A total of 140 children aged 7 to 15 with orthognathic occlusion were examined in accordance with the developed chewing test program in order to assess the efficacy of chewing. Tables of the mean values of the examined parameters were made up with consideration for age. The results evidence that though the general tendency is enhancement of chewing function with age, a decrease of some parameters is observed at the age of 8-10, because of anatomic specificities in this period. The developed method for chewing assessment is simple and rapid and may be widely used in practical dentistry.
Subject(s)
Dental Occlusion , Mastication/physiology , Adolescent , Aging/physiology , Child , Deglutition/physiology , Humans , Methods , Time FactorsSubject(s)
Aging , Dental Arch/anatomy & histology , Dental Occlusion , Adolescent , Adult , Anthropometry/instrumentation , Child , Child, Preschool , Humans , Infant , Models, Dental , Reference ValuesSubject(s)
Altitude , Anemia, Aplastic/blood , Erythrocytes/physiology , Adolescent , Adult , Hemolysis , Humans , Osmotic FragilityABSTRACT
The efficacy of colony-formation of bone marrow fibroblasts was examined in 18 patients with pancytopenia and partial cytopenia, 5 patients with intravascular hemolysis and in 4 patients with iron deficiency anemia before and after staying in mountains at an altitude of 3,200 m. It was shown that during staying in mountains, the efficacy of colony-formation was 2 to 4 times as increased. A difference was noted in the pattern of the growth of fibroblasts in patients with intracellular cytolytic syndromes and intravascular hemolysis and iron deficiency anemia.