ABSTRACT
A case of malacoplakia with a tumor-like involvement of the pelvis is presented. It was characterized by a urine-trickling fistula from the bladder to the gluteal surface and by acute urinary retention. Examinations both cytologic of urine collected from urethra and from fistula, and histological of tissues from bladder and rectum were performed. Histiocytes with Michaelis Gutmann bodies were found in all specimens. The specimens were also studied from an immunohistochemical and electron-microscopic point of view. The case was found interesting because of the unusual fistulization and for the absence of other important associated diseases usually reported in the literature.
Subject(s)
Malacoplakia/pathology , Pelvis/pathology , Fistula/metabolism , Fistula/pathology , Histological Techniques , Humans , Immunohistochemistry , Malacoplakia/metabolism , Male , Microscopy, Electron , Middle Aged , Trypsin/metabolismABSTRACT
A study of 1,798 endometrial cytological samples, obtained with an "endocyte" (a disposable scraping device) and controlled in histology is presented. The method was tested for its usefulness in screening of precancerous lesions and preclinical cancer in 1,248 asymptomatic women and in the diagnosis of endometrial pathology in 550 symptomatic ones. The classification of hyperplasia into benign simplex and complex hyperplasia and atypical hyperplasia was followed; atypical hyperplasia, considered real intraepithelial neoplasia, was included in the positive cases. Histological verification was made chiefly on cell block in asymptomatic cytologically negative cases and either on curettage or hysterectomies in the others. The main endometrial cytological patterns are described. On the basis of findings, considering also endocyte's low cost, effectiveness, and ease of use, we think the method could be usefully employed in screening of endometrial cancer for an asymptomatic population. In symptomatic women, the use of histologic procedures is still preferable, and cytology cannot be considered a "first option" method.
Subject(s)
Adenocarcinoma/prevention & control , Mass Screening/methods , Precancerous Conditions/prevention & control , Uterine Neoplasms/prevention & control , Adenocarcinoma/diagnosis , Adult , Aged , Cytodiagnosis , Female , Humans , Hyperplasia , Middle Aged , Precancerous Conditions/classification , Uterine Neoplasms/classification , Uterine Neoplasms/diagnosisABSTRACT
Two cases of undifferentiated Burkitt's type malignant lymphoma with prevalent ovarian localization and observed in Italy are described histologically. Some brief considerations about the extra African diffusion of this lymphoma are pointed out.
