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1.
Gig Sanit ; (1): 62-4, 2005.
Article in Russian | MEDLINE | ID: mdl-15751307

ABSTRACT

The paper presents the results of investigations on the hygienic standardization of the levels of selenium hexafluoride (SeF6) in the air of a working area. It also analyzes the data on the effects of SeF6 inhalation on laboratory animals, by applying morphological, physiological, hematological, and biochemical studies. The studies have yielded the basic parameters of inhalation toxicity and established the threshold of the irritant action of the substance, developed and approved its maximally acceptable concentration (0.2 mg/m3, gas + vapors) and a procedure for photometric determination of SeF6 in the air of a working area.


Subject(s)
Air Pollutants, Occupational/analysis , Air Pollutants, Occupational/toxicity , Fluorides/analysis , Fluorides/toxicity , Selenium Compounds/analysis , Selenium Compounds/toxicity , Animals , Guinea Pigs , Humans , Inhalation , Maximum Allowable Concentration , Models, Theoretical , Photometry , Rabbits , Rats , Time Factors
3.
Eksp Onkol ; 6(4): 25-8, 1984.
Article in Russian | MEDLINE | ID: mdl-6499746

ABSTRACT

Quantitative changes in phospholipid spectra of blood serum, liver, kidneys and tumour tissues were determined at different stages of carcinogenesis induced by nitrosodimethylamine in rats. It was established that tissue of kidney tumours differs from homologous tissue only in the total amount of phospholipids as well as of cardiolipin phosphatidylethanolamine, phosphatidylserine and sphingomyelin. Essential changes were revealed in the phospholipid spectrum of blood serum and liver of tumour-bearing rats. The inverse correlation was found in phosphatidylethanolamine and phosphatidylserine amount in these tissues.


Subject(s)
Dimethylnitrosamine , Kidney Neoplasms/metabolism , Liver Neoplasms/metabolism , Phospholipids/metabolism , Animals , Kidney/metabolism , Kidney Neoplasms/chemically induced , Liver/metabolism , Liver Neoplasms/chemically induced , Male , Phospholipids/blood , Rats , Time Factors
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