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J Natl Compr Canc Netw ; 11(10): 1187-91, 2013 Oct 01.
Article in English | MEDLINE | ID: mdl-24142819

ABSTRACT

Imatinib mesylate represents a revolution in the management of patients with metastatic gastrointestinal stromal tumors (GISTs). More recently, postoperative imatinib has been shown to improve both disease-free and overall survivals in patients with a high risk of recurrence. This article presents a well-documented case of a patient with painful and reversible bone edema related to imatinib.


Subject(s)
Antineoplastic Agents/adverse effects , Benzamides/adverse effects , Bone and Bones/drug effects , Bone and Bones/pathology , Edema/chemically induced , Piperazines/adverse effects , Protein Kinase Inhibitors/adverse effects , Pyrimidines/adverse effects , Antineoplastic Agents/therapeutic use , Benzamides/therapeutic use , Edema/diagnosis , Gastrointestinal Stromal Tumors/complications , Gastrointestinal Stromal Tumors/drug therapy , Humans , Imatinib Mesylate , Magnetic Resonance Imaging , Male , Middle Aged , Piperazines/therapeutic use , Protein Kinase Inhibitors/therapeutic use , Pyrimidines/therapeutic use , Tomography, X-Ray Computed
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