ABSTRACT
Since 1942, when paracoccidioidomycosis was first identified in the state of Rio Grande do Sul, paracoccidioidal pulmonary lesions became a great concern to physicians. The present study focuses on 53 patients diagnosed over a seven-year period who presented paracoccidioidal lesions circumscribed to the lungs. These patients presented clinical and radiological features that simulated several pulmonary infectious and non-infectious conditions. Four unusual cases are briefly discussed. A sequence of laboratorial tests should be established for the diagnosis of pulmonary paracoccidioidomycosis.
Subject(s)
Lung Diseases, Fungal/diagnosis , Paracoccidioidomycosis/diagnosis , Adult , Biopsy, Needle , Brazil , Bronchoalveolar Lavage , Bronchoalveolar Lavage Fluid/microbiology , Female , Humans , Immunodiffusion , Lung Diseases, Fungal/microbiology , Male , Middle Aged , Radiography, Thoracic , Retrospective Studies , Smoking , Sputum/microbiologyABSTRACT
A case of a solitary pulmonary nodule due to Scedosporium apiospermum (Pseudallescheria boydii) is related. A review of the pertinent literature was done and, in addition, similar lesions caused by other opportunistic fungi are commented.
Subject(s)
Lung Diseases, Fungal/diagnosis , Lung Diseases, Fungal/microbiology , Pseudallescheria/isolation & purification , Solitary Pulmonary Nodule/diagnosis , Solitary Pulmonary Nodule/microbiology , Adult , Female , HumansABSTRACT
Six cases of pulmonary paracoccidioidomycosis diagnosed only by transthoracic fine needle aspiration are presented. The clinical and radiological presentation is varied. The most frequent use of this technique will permit the diagnosis of early lesions of mycosis.
Subject(s)
Agricultural Workers' Diseases/diagnosis , Lung Diseases, Fungal/diagnosis , Paracoccidioides/isolation & purification , Paracoccidioidomycosis/diagnosis , Adult , Agricultural Workers' Diseases/microbiology , Biopsy, Needle/methods , Female , Humans , Lung Diseases, Fungal/diagnostic imaging , Lung Diseases, Fungal/microbiology , Male , Middle Aged , Paracoccidioidomycosis/diagnostic imaging , Paracoccidioidomycosis/microbiology , RadiographyABSTRACT
Two cases of Chronic Pulmonary Histoplasmosis are reported and other eleven cases, collected from Brazilian literature, are commented. After being clinically cured, one of our patients presented an Aspergillus fungus ball inside a cavitation in the wall of which H. capsulatum was disclosed. Comments are also done on the diagnosis of the mycosis.
Subject(s)
Histoplasmosis/pathology , Lung Diseases, Fungal/pathology , Aged , Aspergillus fumigatus/isolation & purification , Biopsy, Needle/methods , Brazil , Chronic Disease , Histoplasma/isolation & purification , Histoplasmosis/diagnostic imaging , Humans , Lung Diseases, Fungal/diagnostic imaging , Male , RadiographyABSTRACT
In this study we have compared clinical data obtained from 40 reported cases of pulmonary Aspergillus niger intracavitary colonization in the literature and those of our series 23 cases. Additionaly six of our cases have been summarized. Our findings revealed a similar occurrence of male sex, active tuberculosis, diabetes mellitus, systemic oxalosis, and lethal outcome in both groups. In conclusion, A. niger is not the most frequent causative agent of saprophytic aspergillosis neither is the most pathogenic species of Aspergillus. Despite that, when pulmonary A. niger intracavitary colonization is associated with diabetes the prognosis is generaly poor, probably due to acute oxalosis.
