ABSTRACT
The improvement of combined anesthesia is associated with the improvement of its control. The latter is possible only with continuous administration of anesthetics. 130 procedures of combined anesthesia were performed in patients subject to abdominal and other types of operations. With this in view fentanyl and calipsol were continuously injected, using modified dosators, to patients pretreated with N2O and total curarization. It has been found that with continuous administration adequate analgesia with stable blood pressure can be achieved provided that 1/3-2/3 of the total fentanyl dose is used as a loading dose at the beginning of anesthesia. The maintenance dose does not change considerably blood anesthetic concentration. If required, changes in the concentrations were achieved by additional fentanyl administration, using a dosator for 25-50 mukg. The technique described has advantages over bolus drug injection and continuous drug infusion. The technique may be considered a controlled one.
Subject(s)
Anesthesia, General/methods , Anesthetics/administration & dosage , Fentanyl/administration & dosage , Ketamine/administration & dosage , Humans , Surgical Procedures, OperativeABSTRACT
The wearable drug pump HDL-2M has been clinically tested. It is of small dimensions, high reliability and easy-to-use. By means of the unit insulin was administered to patients suffering from insulin-dependent diabetes mellitus. With the HDL-2M, the therapy of the diabetes has been shown to be more effective than the traditional hypodermic injections because it allows a rapid glycemia normalization with less insulin dosage, as a rule, and a considerable decrease in glycemia lability. The numerous tests demonstrate that the HDL-2M can be extensively and successfully used for therapy of insulin-dependent diabetes mellitus in clinical practice.
