[Characteristic features of erythrocyte aggregation in different animals and in man]. / Osobennosti aggregatsii éritrotsitov u raznykh zhivotnykh i cheloveka.

The reversible erythrocytes aggregation is considered to be a basic microrheological process determining a number of microcirculation features. But the problem of the adaptive role of erythrocytes aggregation still needs elucidation. The markedness of erythrocytes aggregation was compared in mammals occupying different positions in the evolutionary systematics: in 62 animals of 10 species and in 25 healthy humans. The species features of the erythrocytes aggregation were altered by means of adding high--molecular polyoxyethylene to blood plasma. The data obtained gave evidence on species differences in the erythrocytes aggregation, specifics of cell membrane, differences in the latter's electrostatic charge.

[Effect of polyethylene oxides on erythrocyte aggregation]. / Vliianie poliétilenoksidov na agregatsiiu eritrotsitov.

The effect of polyethylene oxide of different molecular weight on the aggregation of erythrocytes has been investigated. It was shown that the addition to blood of polymers with molecular weight of 600 and 1 000 weakens this aggregation, whereas the addition of those with molecular weights of 4 000 and 6 000 completely prevents it, simultaneously decreasing their osmotic resistance. Polyethylene oxide with molecular weight from 20 000 to 1 000 000 increase the aggregation of erythrocytes and do not affect their osmotic resistance. The aggregation of erythrocytes is a reversible process. The decrease in polyethylene oxide concentration leads to decreasing aggregation effect. The mechanism of the effect of polymers on cell aggregation is discussed.