ABSTRACT
A sociological survey of 240 clinical laboratory workers and 350 patients could reveal the most important problems in the extra-analytical phase of a laboratory process: the level of computerization of laboratories; the application of a closed vacuum blood sampling system; a need for improving the interaction between laboratory service specialists and clinicians; the necessity for laboratory diagnosis specialists to hold lectures and seminars for clinicians; inadequate interaction between patients and attending physicians; a patient's failure to follow the study preparation instructions; a patient's dissatisfaction with a process of drawing up a referral protocol for laboratory studies; and a queue for biomaterial sampled for laboratory studies.
Subject(s)
Clinical Laboratory Techniques/standards , Laboratories/standards , Blood Preservation/standards , Data Collection , Education, Continuing , Humans , Information Systems/standards , Medical Laboratory Personnel/standards , Patient Satisfaction/statistics & numerical data , Physicians/standards , Quality Control , RussiaSubject(s)
Adrenocorticotropic Hormone/analogs & derivatives , Cytokines/biosynthesis , Drug Evaluation, Preclinical/methods , Oligopeptides/pharmacology , Peptide Fragments/pharmacology , Th1 Cells/metabolism , Adolescent , Adrenocorticotropic Hormone/pharmacology , Adult , Chlamydia Infections/drug therapy , Cytomegalovirus Infections/drug therapy , Hepatitis C/drug therapy , Herpes Genitalis/drug therapy , Humans , Influenza, Human/drug therapy , Mycoplasma Infections/drug therapy , Oligopeptides/therapeutic use , RNA, Messenger/metabolism , Respiratory Tract Infections/drug therapy , Th1 Cells/drug effects , Tuberculosis/drug therapySubject(s)
Antiviral Agents/pharmacology , Oligopeptides/pharmacology , Peptides/chemistry , Animals , Chlorocebus aethiops , Chromatography/methods , Dogs , Encephalomyocarditis virus/metabolism , Glycine/chemistry , Humans , Mass Spectrometry/methods , Mice , Oligopeptides/chemistry , Proline/chemistry , Vero CellsABSTRACT
Herpesvirus type 8 or Kaposi's sarcoma-associated virus has been recently discovered and it is an etiologic agent of several known diseases. It has common features that link it with other representatives of the family Herpesviridae: similar structural elements and genomic organization, and the common mechanisms of replication. Nevertheless, this virus has a number of unique features that make it an interesting matter for investigations and currently central in modern medicine and biology. This overview is to draw attention to this representative of herpesviruses and to outline some epidemiological, pathogenetic, and molecular aspects of this problem.
