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1.
Mycobacterium bovis BCG-Russia clinical isolate with noncanonical spoligotyping profile.
Mokrousov, Igor; Vyazovaya, Anna; Potapova, Yulia; Vishnevsky, Boris; Otten, Tatiana; Narvskaya, Olga.
J Clin Microbiol ; 48(12): 4686-7, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20881181

Subject(s)
Mycobacterium bovis/genetics , Mycobacterium bovis/isolation & purification , Tuberculosis/diagnosis , Tuberculosis/microbiology , Child , Child, Preschool , DNA Fingerprinting , Humans , Infant , Male , Molecular Typing , Mycobacterium bovis/classification , Russia
2.
Molecular characterization of ofloxacin-resistant Mycobacterium tuberculosis strains from Russia.
Mokrousov, Igor; Otten, Tatiana; Manicheva, Olga; Potapova, Yulia; Vishnevsky, Boris; Narvskaya, Olga; Rastogi, Nalin.
Antimicrob Agents Chemother ; 52(8): 2937-9, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18559646

ABSTRACT

In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the Beijing genotype in a local population of M. tuberculosis.


Subject(s)
Bacterial Proteins/genetics , Mycobacterium tuberculosis/drug effects , Ofloxacin/pharmacology , Tuberculosis, Multidrug-Resistant/genetics , Antitubercular Agents/pharmacology , Bacterial Proteins/metabolism , DNA Gyrase/genetics , DNA Gyrase/metabolism , Genotype , Mycobacterium tuberculosis/enzymology , Mycobacterium tuberculosis/genetics , Russia
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