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1.
J Int Med Res ; 46(6): 2186-2201, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29614897

ABSTRACT

Objectives To evaluate the effect of oral nutritional supplementation (ONS) plus dietary counselling (DC) (intervention) versus DC alone (control) on growth and upper respiratory tract infection (URTI) in nutritionally at-risk, picky eating children in India. Methods We performed a 90-day, prospective, randomized, controlled trial. A total of 255 children aged 24-72 months with a weight-for-age z-score ≥-2 and <-1, picky eating behaviour, and acute URTI were randomized to the control (n = 128) or intervention group (n = 127). The outcomes included the change in weight-for-age z-score from days 1 to 90 and the URTI incidence. Results The mean age was 44.0 ± 14.3 months. The intervention group showed a significantly greater increase in mean weight-for-age and body mass index-for-age z-scores compared with the control group from day 10 onwards. Higher energy intake in the intervention group was observed at all follow-up visits, except for day 10. The incidence of URTI in the control group was 2.01 times higher than that in the intervention group, controlling for confounding factors. Conclusions ONS plus DC is effective for improving weight and reducing the incidence of URTI in nutritionally at-risk, picky eating children with an acute URTI episode.


Subject(s)
Child Development , Child Nutrition Disorders/therapy , Dietary Supplements , Feeding and Eating Disorders/therapy , Respiratory Tract Infections/prevention & control , Administration, Oral , Child , Child Development/physiology , Child Nutrition Disorders/physiopathology , Child, Preschool , Counseling , Energy Intake , Feeding Behavior , Feeding and Eating Disorders/complications , Feeding and Eating Disorders/physiopathology , Female , Growth Charts , Humans , Male , Nutritional Status , Prospective Studies , Recurrence , Respiratory Tract Infections/etiology , Risk Factors
2.
J Int Med Res ; 46(7): 2615-2632, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29695211

ABSTRACT

Objectives To evaluate the 120-day post-intervention growth trajectory of picky-eating children aged 2 to 6 years who previously completed a 90-day, randomized, controlled trial of oral nutritional supplementation (ONS) plus dietary counselling (DC) (SDC, n = 98) compared with DC alone (n = 105). Methods A total of 203 children were included. Children were free to consume ONS during follow-up. Information on ONS consumption was collected. Weight-for-age percentile (WAP) and height-for-age percentile (HAP) were measured at Day 90 (beginning) and Day 210 (end point). Results Despite continued weight gain, there was a significant decline in WAP in both groups during the post-intervention period. However, children who took ONS voluntarily had a smaller loss in WAP compared with those who did not. Children in the SDC group showed no difference in a decline in HAP between those who took ONS during follow-up and those who did not. However, children in the DC group showed a marginally larger decline in HAP in those who did not take ONS during the follow-up compared with those who did. Conclusions Continued parental self-administration of ONS to their children slows down the loss of growth percentiles, supporting continued weight gain in picky-eating children at nutritional risk.


Subject(s)
Child Nutrition Disorders/therapy , Dietary Supplements , Enteral Nutrition/methods , Feeding Behavior , Feeding and Eating Disorders/therapy , Body Height , Body Weight , Body-Weight Trajectory , Child , Child Development , Child Nutrition Disorders/diagnosis , Child, Preschool , Counseling , Energy Intake , Feeding and Eating Disorders/diagnosis , Female , Follow-Up Studies , Growth Charts , Humans , Male , Prospective Studies , Self Care , Weight Loss
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