Subject(s)
Antimetabolites, Antineoplastic/adverse effects , Fluorouracil/adverse effects , Wernicke Encephalopathy/chemically induced , Antimetabolites, Antineoplastic/therapeutic use , Ataxia/chemically induced , Colonic Neoplasms/drug therapy , Confusion/chemically induced , Fluorouracil/therapeutic use , HumansSubject(s)
Colitis/chemically induced , Diosmin/adverse effects , Aged , Chronic Disease , Colitis/immunology , Diarrhea/etiology , Female , Humans , LymphocytesSubject(s)
Hemochromatosis/diagnosis , Liver Abscess/microbiology , Yersinia pseudotuberculosis Infections/complications , Aged , Biopsy , Ferritins/blood , Genotype , Hemochromatosis/complications , Hemochromatosis/genetics , Humans , Iron/blood , Liver/pathology , Liver Abscess/diagnosis , Magnetic Resonance Imaging , Male , Mutation/genetics , Yersinia pseudotuberculosis/isolation & purification , Yersinia pseudotuberculosis Infections/diagnosisABSTRACT
An observation of chronic ulcerative ileo-jejunitis associated with a hemophagocytic syndrome leading to death is described. It was not associated with coeliac disease. The hemophagocytic syndrome had no other etiology than chronic ulcerative ileo-jejunitis. The relations between these two disorders are discussed.
Subject(s)
Enteritis/complications , Histiocytosis, Non-Langerhans-Cell/etiology , Ileal Diseases/complications , Jejunal Diseases/complications , Ulcer/complications , Adult , Chronic Disease , Enteritis/pathology , Fatal Outcome , Histiocytosis, Non-Langerhans-Cell/pathology , Humans , Ileal Diseases/pathology , Jejunal Diseases/pathology , Male , Ulcer/pathologyABSTRACT
OBJECTIVES: Spontaneous chest pain attacks are uncommon during 24-hour esophageal pH monitoring in patients suffering from angina-like chest pain suspected to be acid-related. The aim of this study was to assess the diagnostic value of exertional esophageal pH monitoring and to prove that exercise testing induces chest pain and gastro-esophageal reflux and therefore improves symptomatic correlation study. METHODS: Forty three patients suffering from angina-like chest pain underwent treadmill exercise testing during a 24-hour esophageal pH monitoring. Symptom analysis was made using the symptom-association probability described by Weusten. RESULTS: During the 24-hour pH monitoring, 10 patients (23%) had a pathologic esophageal acid exposure, 20 (46%) experienced chest pain and 3 (7%) had a symptom association probability > 95%. During the exercise testing on a treadmill, 19 patients (44%) had gastro-esophageal reflux, and 14 (32%) experienced chest pain, coinciding with a gastro-esophageal reflux in 8 (19%). After exercise testing, the symptom-association probability analysis was significantly changed in 9 patients (21%), > 95% in 6 patients (14%). CONCLUSION: Exercise testing on a treadmill induces chest pain episodes during a 24-hour esophageal pH monitoring and therefore improves symptomatic correlation study in patients suffering from angina-like chest pain.