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J Invest Dermatol ; 127(5): 995-7, 2007 May.
Article in English | MEDLINE | ID: mdl-17435784

ABSTRACT

ErbB3 receptor is a member of the epidermal growth factor (EGF) receptor (ErbB1) family. Okwueze et al. have transfected this receptor in a pig model of wounds and demonstrate that it accelerates the resurfacing of the wounds when combined with epiregulin or heparin-binding EGF. Currently, only hypotheses can be proposed to explain the observations.


Subject(s)
Receptor, ErbB-3/physiology , Wound Healing/physiology , Animals , Cell Proliferation , Epidermal Growth Factor/physiology , Epiregulin , Heparin-binding EGF-like Growth Factor , Intercellular Signaling Peptides and Proteins , Keratinocytes/physiology , Models, Animal , Swine
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