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1.
BMJ Case Rep ; 14(4)2021 Apr 01.
Article in English | MEDLINE | ID: mdl-33795274

ABSTRACT

An 18-year-old woman was treated for acute kidney injury (AKI) secondary to antiglomerular basement membrane (GBM) disease with prednisolone, cyclophosphamide and plasma exchange. She also had epistaxis at initial presentation with no other organ involvement and achieved good recovery of her kidney function. Two weeks after completing induction treatment, she re-presented with further AKI and pulmonary haemorrhage. She was recommenced on plasma exchange and steroids and was given rituximab. She recovered from her illness with significant improvement to her kidney function. The cause of her relapse was thought to be possibly due to the use of hair dye. This case highlights the importance of acknowledging potential environmental exposures to prevent relapses of disease. We were also able to demonstrate a case of successful treatment of anti-GBM disease with rituximab.


Subject(s)
Anti-Glomerular Basement Membrane Disease , Hair Dyes , Adolescent , Anti-Glomerular Basement Membrane Disease/chemically induced , Anti-Glomerular Basement Membrane Disease/drug therapy , Cyclophosphamide/adverse effects , Female , Humans , Neoplasm Recurrence, Local , Rituximab/adverse effects
2.
BMJ Open Qual ; 7(1): e000045, 2018.
Article in English | MEDLINE | ID: mdl-29527575

ABSTRACT

BACKGROUND: The surgical post-take ward round is a complex multidisciplinary interaction in which new surgical patients are reviewed and management plans formulated. Its fast-paced nature can lead to poor communication and inaccurate or incomplete documentation with potential detriment to patient safety. Junior team members often do not fully understand the diagnosis and management plan. AIMS: The aims of this project were to improve both communication and documentation on the surgical post-take ward round, influencing patient safety. METHODS: The ward round was deconstructed to identify individual roles and determine where intervention would have the most impact. Ten important points were identified that should be documented in the management of an acute surgical patient; observations, examination, impression, investigations, antibiotics, intravenous fluids, VTE assessment, nutrition status, estimated length of stay and ceiling of treatment. A 'Take Ten' checklist was devised with these items to be used as a 'time out' after each patient with the whole team for discussion, clarification and clear documentation. Four plan do study act cycles were completed over a period of a year. A retrospective review of post-take documentation preintervention and postintervention was performed, and the percentage of points that were accurately documented was calculated. For further clarification, 2 weekends were compared-one where the checklist was used and one where it was not. RESULTS: Results showed documentation postintervention varied between categories but there was improvement in documentation of VTE assessment, fluids, observations and investigations. On direct comparison of weekends the checklist showed improved documentation in all categories except length of stay. Junior team members found the checklist improved understanding of diagnosis and management plan, and encouraged a more effective ward round. CONCLUSION: The 'Take Ten' checklist has been well received. Three years on from its inception, the checklist has become an integral part of the post-take ward round, thanks to the multidisciplinary engagement in the project.

3.
J Arthroplasty ; 30(10): 1799-803, 2015 Oct.
Article in English | MEDLINE | ID: mdl-25981328

ABSTRACT

Controversy exists regarding the amount of acetabular bone resection, biomechanics and function of patients receiving either total hip arthroplasty (THA) or hip resurfacing arthroplasty (HRA). A cohort of patients undergoing 36 mm ceramic-on-ceramic THA (89) or metal-on-metal HRA (86) were compared. No difference was observed when the ratio of native femoral head size was compared to the implanted acetabular component size (1.15 ± 0.1 HRA c.f. 1.13 ± 0.1 THA). No difference was observed in acetabular offset, vertical centre of rotation or function (OHS mean 47 in both groups) but leg length discrepancy (1.8 mm c.f. 5.5 mm) and femoral offset did differ (0.6 mm c.f. 4.1 mm). This demonstrates that 36 mm ceramic-on-ceramic THA is not associated with more bone resection than HRA and achieves equivalent function whilst avoiding the problems of metal-on-metal bearings.


Subject(s)
Acetabulum/surgery , Arthroplasty, Replacement, Hip/instrumentation , Arthroplasty, Replacement, Hip/methods , Hip Prosthesis , Leg Length Inequality/surgery , Leg/surgery , Adult , Aged , Ceramics , Female , Femur/surgery , Femur Head/surgery , Hip Joint/diagnostic imaging , Humans , Male , Metals/chemistry , Middle Aged , Postoperative Period , Radiography , Retrospective Studies , Rotation
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