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J Vis Exp ; (208)2024 Jun 28.
Article in English | MEDLINE | ID: mdl-39007604

ABSTRACT

Pineal neoplasms have a significant impact on children although they are relatively uncommon. They account for approximately 3-11% of all childhood brain tumors, which is considerably higher than the <1% seen in adult brain tumors. These tumors can be divided into three main categories: germ cell tumors, parenchymal pineal tumors, and tumors arising from related anatomical structures. Obtaining an accurate and minimally invasive tissue diagnosis is crucial for selecting the most appropriate treatment regimen for patients with pineal gland tumors. This is due to the diverse treatment options available and the potential risks associated with complete resection. In cases where patients present with acute obstructive hydrocephalus caused by a pineal gland tumor, immediate treatment of the hydrocephalus is necessary. The urgency stems from the potential complications of hydrocephalus, including increased intracranial pressure and neurological deficits. To address these challenges, a minimally invasive endoscopic approach provides a valuable opportunity. This technique allows clinicians to promptly relieve hydrocephalus and obtain a histological diagnosis simultaneously. This dual benefit enables a more comprehensive understanding of the tumor and assists in determining the most effective treatment strategy for the patient.


Subject(s)
Brain Neoplasms , Pineal Gland , Pinealoma , Ventriculostomy , Humans , Ventriculostomy/methods , Pineal Gland/surgery , Pineal Gland/pathology , Pinealoma/surgery , Pinealoma/pathology , Brain Neoplasms/surgery , Brain Neoplasms/pathology , Biopsy/methods , Hydrocephalus/surgery , Hydrocephalus/pathology , Third Ventricle/surgery , Third Ventricle/pathology , Neuroendoscopy/methods
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